| The Letter/Hint | Answer |
| N (The medical speciality of Dr. Foreman) | |
| O (The actress who plays '13' on the show) | |
| P (The name of the hospital where the show takes place) | |
| Q (Steve Mc____ [The name of House's pet rat]) | |
| R (The actor who plays Wilson) | |
| S (House is an avid watcher of these types of television shows) | |
| T (The name of opening theme song on the show which is performed by the group 'Massive Attack') | |
| U (Cuddy was in undergrad at this school at the same time House was in its medical school) | |
| V (House is addicted to this drug) | |
| W (Considered House's best friend; oncologist at the hospital) | |
| X (House or any of the other doctors will sometimes order this procedure to get a look inside of a patient's body) | |
| Y (This 'Rolling Stones' song made multiple appearances in the show, including when Amber quotes the title to House in the season 4 finale) | |
| Z ('Chasing _____, Circling the Drain'...This was supposed to be the show's name before it was changed to 'House'. | |