| Character Info | Character Name |
| Black detective who scales the ranks despite questionable past; gets divorced but keeps it private to help wife's political career | |
| Polish American Head of Dock workers union; smuggles items to help raise money to promote dock; is going to snitch but gets killed and dumped in water | |
| Son of dock head; helps smuggle but is a clown; bring duck to a bar; kills a man in store and breaks down before being arrested | |
| Renowned stick up man who constantly robs drug dealers; although homosexual everyone is scared of him | |
| Drug Kingpin of Eastside; runs pawn shop where he fixes items; very fat | |
| Druge Kingpin who runs the Organization; goes to jail several times | |
| White Detective known for drinking, having affairs & aggresive attitude | |
| Black homicide detective; drinks, has affiars & always smokes cigar; played lacrosse | |
| Young corner boy with bad mouth; kills major criminal in store | |
| Young black cop who constantly works undercover; when unit shutdown investigates political corruption | |
| Big white cop who works main case, catches mayor getting BJ; eventually fired & works for lawyer | |
| Corner boy who starts using drugs; moves to the country then gets killed by friends for snitching | |
| Old Polish American Police Captain;son-in-law fired from force; fights for stain glass window in church | |
| Corner boy; loves the ladies; kills friend in season one | |
| Nephew of Barksdale Organization leader; killed in jail in fake suicide | |
| Top soldier of Barksdale Orginzation; goes to jail for multiples murders; son becomes dealer; loves his fish tank | |
| Student who is son of former Barksdale soldier who starts to sell drugs; stops dealing & moves in with former cop | |
| Head soldier of Stanfield org who commits many murders and hides bodies in empty rowhouses; is eventually arrested | |
| Lesbian detective who gets shot while undercover | |
| #2 of smuggling operation at the docks; often holds meetings at diner; major drug supplier for Co-op | |
| Black cop who works street for years including 'Hamsterdam'; matures & helps kids | |
| White lawyer who represents most criminals | |
| Nephew of drug kingping; is involved in dog fighting; betrays uncle and is eventually killed | |
| White councilman who eventually becomes Mayor | |
| Smart student from poor family; eventually turns to drugs | |