Science / Renal Pathology

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Can you name the Renal/Urinary Diseases?

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HintDiseaseDisease Type
Broad-based irregular scarring with or without chronic inflammation; may lead to death from uremia, end-stage kidneyInterstitial Disease
Results in finely granular surface due to arteriolonephrosclerosis; can lead to accelerated arteriosclerosis, LVH, retinal damage, and kidney failureRenal Vascular Disease
Abnormality in IgA production and clearance; variant of Henoch-Schoenlein purpura; most commonly biopsy diagnosed glomerular diseaseGlomerular Disease
Sessile infiltrating tumor with necrosis and ulceration of the lining; metastasis is usually late and not extensiveLower Urinary Tract Disease
Variable end-stage clinical complex due to abnormal retention or excretion of electrolytes and toxic waste productsRenal Failure
Children after strep throat; immune complexes; hypercellular glomeruli; subepithelial humpsGlomerular Disease
Caused by immune complex disease; 5-10% of all nephritic symptoms, most common in 2nd decadeGlomerular Disease
Proteinuria, hypoalbuminemia, hyperlipidemia, lipiduria, and severe edema; due to derangement in glomerular capillary wallsRenal Failure
Causes are idiopathic, recurrent or smoldering acute GN; may be asymptomatic for yearsGlomerular Disease
Two types: anoxic/ischemic (‘shock’ kidney) or toxic (mercury, carbon tetrachloride, or ethylene glycol)Other
Inflammation due to ascending or descending infection, instrumentation, antiseptics, calculi, foreign bodies, obstruction, bubble bath, pregnancy, or ‘honeymoon’ cystitisLower Urinary Tract Disease
Includes acute nonbacterial, chronic nonbacterial, and acute bacterial varietiesInterstitial Disease
5-10% of all pregnancies; proteinuria, edema, hyperreflexia, hypertension; return to normal with delivery of the placentaGlomerular Disease
Abscesses; usually benign and self-limited lasting less than a week; may lead to death due to sepsis with or without renal failureInterstitial Disease
Cancer of embryonic renal cells; abdominal mass, fever and hypertension in 50% of casesRenal Tumor
Primary or secondary, may follow other GNs, HIV, heroin addiction; some glomeruli show partial hyalinizationGlomerular Disease
Caused by Goodpasture’s syndrome, unresolved acute GN, or is idiopathic; death from renal failure in 3-12 monthsGlomerular Disease
Painless hematuria, but may also see flank pain, fever, abdominal mass, and metastasis to lung or boneRenal Tumor
Acute inflammation involving all glomeruli; due to immune complex deposits in the glomeruliGlomerular Disease
HintDiseaseDisease Type
Autoimmune disease of medium and small arteriesRenal Vascular Disease
Fairly common congenital defect; may cause renal failure in infancy or adulthood resulting from pressure atrophyOther
Usually from embolism from the heart in RF or SBE, atrial fib, or mural thrombosis after MIRenal Vascular Disease
Very high systolic and diastolic pressures, papilledema, encephalopathy, and rapid renal failure; fibrinoid necrosis, ‘onion skinning’ and ‘fleabitten’ kidneysRenal Vascular Disease
Dilation of renal pelvis and associated atrophy of renal tissue due to obstruction; amount of damage depends on degree and duration of the obstructionOther
Major cause of nephritic syndrome in children; electron microscopy reveals flattening and fusion of the foot processes of epithelial cellsGlomerular Disease
End-stage of many renal diseases; small contracted kidneys, diffuse, global hyaline sclerosis of glomeruli accompanied by marked tubular atrophy, patchy interstitial fibrosis, and Glomerular Disease
Grossly visible hematuria, hypertension, azotemia, oliguria, mild edema, red blood cell casts, and variable proteinureaRenal Failure
Arteriosclerotic involvement of large and medium intrarenal arteries; results in V-shaped depressed areas on kidney surfaceRenal Vascular Disease
Urinary stone; caused by chemical salt precipitation in the urine; most associated with idiopathic hypercalciuriaOther
Combination of acute pyelonephritis and ischemia causing necrosis of renal papillae; almost always in diabeticsInterstitial Disease
Tumors, vesicoureteral reflux, or ureteritis cause this ureter problemLower Urinary Tract Disease
Bacterial infection of both renal parenchyma and renal pelvisInterstitial Disease
Caused by immune complex disease; major cause of nephrotic symptoms in adults; onset is insidious, with a prolonged courseGlomerular Disease
Can be caused by antibiotics and NSAIDs; IgE and T-cell-mediated immune reaction; fever, eosinophilia, hematuriaInterstitial Disease
Includes agenesis and hypoplasia, fusion, duplication of the ureters, anomalies of the renal vessels, and horseshoe kidneysOther
Causes include bacterial endocarditis, systemic bacterial infections, immune glomerular diseases, DIC, or it can be idiopathicGlomerular Disease
Due to prostatic hypertrophy or carcinoma, strictures, tumor, calculus, neurogenic bladder, or posterior urethral valvesLower Urinary Tract Disease
Arteriolar nephrosclerosis with hypertension; Kimmelstiel-Wilson Disease; acute or chronic pyelonephritisRenal Vascular Disease

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