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| the diagnostic rash of lyme disease, bull's eye appearance, usually nontender and indicative of first stage infection | |
| this family of ticks is the vector for lyme disease | |
| Diagnosis: Areas of multiplication are characterized by necrosis or granuloma production | |
| Lesser virulence factor of lyme disease, causes autoimmune response and antigenic variation | |
| Diagnose: a facultative intracellular pathogen infects reticuloendothelial organs, multiplies in macrophages, | |
| septicemic plague is notably absent of | |
| Pathogen: gram -, rods, bipolar staining | |
| this type of plague is highly contagious | |
| Lyme disease: this second test is more specific | |
| treatment: 2 drugs for tularemia | |
| During Direct immunofluorescence, F1 antigen is a sign of this virulence factor in plague | |
| a deer fly can transmit this disease | |
| RMSF prefers to infect this type of cell | |
| dark discoloration, black death describes this type of plague | |
| Diagnose: this disease causes increased vasculitis, thrombosis, and vascular permeability | |
| Pathogen: tularemia | |
| relapsing fever is due to this borrelia | |
| This pathogen is a spirochete | |
| Injected YOPs suppress production of ______, interfering with immune system messaging | |
| treatment: 2 drugs for lyme disease | |
| A flea bite can cause transmission of this disease | |
| higher incidence of Lyme disease occurs at the end of this season | |
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| Pathogen: gram -, coccobacilli, obligate intracellular, thin murein layer | |
| For RMSF, this is the most rapid and specific diagnostic assay | |
| Diagnose: preferentially infect endothelial cells lining the small blood vessels | |
| Lyme disease: this is the first step of sensitive testing | |
| YOP | |
| For RMSF, this process detects bacteria in the skin biopsy of the rash | |
| For RMSF, this is the most frequently used way of measuring rising antibody titer by the first week of illness | |
| In plague, this virulence factor prevents opsonization and phagocytic migration | |
| You would use microscopy during a febrile period to diagnose this borrelial infection | |
| Diagnose: man touched dead rabbits, fever, muscle aches, dry cough, small gram negative rods | |
| Pathogen: plague | |
| Def: piece of dead tissue that is about to slough off the surface of the skin | |
| infection caused by the transmission of microorganisms that naturally live in animals | |
| Diagnose: fever, rash, previous tick bite are important to diagnosing | |
| contact dependent secretion, forms pore in eukaryotic cell membrane, injects toxic proteins directly into eukaryotic cells | |
| wild rodents are responsible for this cycle of the plague | |
| Def: hemorrhagic suppurative lymphadenitis | |
| This is the leading vector borne disease in the US | |
| Lyme disease, second stage: early dissemination can result in abnormalities of these two systems | |
| Plague endotoxins can cause this kind of shock | |
| Pathogen: lyme disease | |
| Diagnose: sudden onset, nonspecific flu like, later rash, petechial, hemorrhageic, first on extremities, spread centripetally to the entire body | |
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| This disease is caused by a facultative intracellular parasite, can affect the eyes, lungs, blood, and gi, caused by gram - rods | |
| Diagnose: in a gram stain, you find bipolar stained rods | |
| treatment: 2 drugs for plague | |
| Diagnose: male died while carrying out an autopsy on a mountain lion, flu like symptoms first | |
| major virulence mechanism of relapsing fever | |
| These are two virulence factors important for dissemination of the plague bacteria | |
| cultures of this bacteria are highly infectious | |
| late lyme disease is shown with fluctuating _________, including joint pain | |
| treatment: ricketts | |
| this test is recommended for later stages of Lyme disease | |
| this family of tick is the vector for rickettsii | |
| When injected by plague, these proteins can have a cytotoxic effect. | |
| Pathogen: gram -, coccobacilli, | |
| treatment: relapsing fever | |
| These three diseases can be transmitted by hard shell ticks | |
| Pathogen: rocky mountain spotted fever | |
| tularemia's anti phagocytic component | |
| most common form of tularemia 75% cases, low mortality | |
| Virulence factor: antiphagocytic part of plague | |
| major virulence factor of lyme disease, causes inflammation | |
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