Can you name the Lin Day 1?

created by Sheppard
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The effects of WISN are caused by a decrease in activity of this protein0
Factor VIII0
Serine protease inhibitor that inhibits plasmin0
Factor II0
isolated from leech saliva, bivalent irreversible thrombin inhibitor0
heparin should not be given to pregnant or breast feeding because of this solution0
clopidogrel and ticlopidine act on this receptor0
DTI used for HIT, beware of liver, increases INRs0
HIT0
irudin and gatro are suffixes for this class0
Factor VII 0
UFH0
These three bivalent DTIs also bind to the substrate site0
Factor I0
These factors facilitate clotting0
heparin can clear lipemia by increasing the level of this enzyme0
Factor X0
enoxaparin, dalteparin, and tinzaparin are types of this drug0
This anticoagulant can cross the placenta and cause hemorrhage and serious birth defect in the fetus0
these blood disorders are treated by anticoagulants0
Factor IV0
recombinant form of hirudin used for HIT, beware of renal insufficiency0
This vitamin K antagonist inhibits epoxide reductase0
a synthetic pentasaccharide with long half life, indirect thrombin inhibitor0
This proteins free form acts as a cofactor to protein C0
Long half life, low side effects, less frequent dosing are traits of this heparin modification0
if the pt has HIT, switch to this drug0
This drug is a mixture of sulfated mucopolysaccharides extracted from porcine gut or bovine lung0
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these vitamin facilitate clotting0
ATIII inactivates these 3 clotting factors (answer in numerical order)0
This LMWH is administered in mg, as opposed to anti factor Xa units0
this drug, mediated by antithrombin, inactivates many intrinsic clotting factors, especially IIa and Xa0
Direct Thrombin Inhibitor, an oral prodrug0
This parenterally administered drug should not be used intramuscularly0
the famous indirect thrombin inhibitor, can induce thrombocytopenia0
This racemic mixture has a long halflife and has 100% bioavailability0
synthetic form of heparin0
allergy, alopecia, and osteoporosis are secondary side effects of this drug0
this enzyme degrades many blood plasma proteins, most notably, the clot0
this antagonist is used to reverse heparin0
Serine protease inhibitor that inactivates clotting factors0
low platelet count, new thrombus, and thrombocytopenia should make you suspicious of this side effect of a indirect thrombin inhibitor0
Factor IX0
Vitamin K dependent glycoprotein, has two forms, free and c4b bound0
These proteins are endogenous anticoagulants0
Degrades cofactor Va and VIIIa, deficiency in this protein can result in increased thrombosis0
WISN0
abciximab and eptifibatide and tirofiban act on this receptor0
A vit K dependent serine protease that is activated by thrombin to APC0
a bivalent reversible thrombin inhibitor that inhibits platelet activation, administered with IV, rapid on/off action0
heparin's half life in hours0
Low molecular weight heparin inhibits this factor0
the oral standard long term therapy0
Blocks the gamma carboxylation of the glutamate residue in prothrombin (II), VII, IX, X, protein C and S0
This occurs if heparin is given intramuscularly0
use the aPTT to measure the drug use0
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Lin Day 1 Quiz

  1. by Sheppard
  • Created Nov 24, 2010 in Science
  • Game Plays 28

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  1. lin

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