| x | x | x |
| these vitamin facilitate clotting | |
| ATIII inactivates these 3 clotting factors (answer in numerical order) | |
| This LMWH is administered in mg, as opposed to anti factor Xa units | |
| this drug, mediated by antithrombin, inactivates many intrinsic clotting factors, especially IIa and Xa | |
| Direct Thrombin Inhibitor, an oral prodrug | |
| This parenterally administered drug should not be used intramuscularly | |
| the famous indirect thrombin inhibitor, can induce thrombocytopenia | |
| This racemic mixture has a long halflife and has 100% bioavailability | |
| synthetic form of heparin | |
| allergy, alopecia, and osteoporosis are secondary side effects of this drug | |
| this enzyme degrades many blood plasma proteins, most notably, the clot | |
| this antagonist is used to reverse heparin | |
| Serine protease inhibitor that inactivates clotting factors | |
| low platelet count, new thrombus, and thrombocytopenia should make you suspicious of this side effect of a indirect thrombin inhibitor | |
| Factor IX | |
| Vitamin K dependent glycoprotein, has two forms, free and c4b bound | |
| These proteins are endogenous anticoagulants | |
| Degrades cofactor Va and VIIIa, deficiency in this protein can result in increased thrombosis | |
| WISN | |
| abciximab and eptifibatide and tirofiban act on this receptor | |
| A vit K dependent serine protease that is activated by thrombin to APC | |
| a bivalent reversible thrombin inhibitor that inhibits platelet activation, administered with IV, rapid on/off action | |
| heparin's half life in hours | |
| Low molecular weight heparin inhibits this factor | |
| the oral standard long term therapy | |
| Blocks the gamma carboxylation of the glutamate residue in prothrombin (II), VII, IX, X, protein C and S | |
| This occurs if heparin is given intramuscularly | |
| use the aPTT to measure the drug use | |