Myeloproliferative Disorders - Mahmoud

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When JAK2 is mutated, cells become abnormally sensitive to this glycoprotein hormone
Excessive histamine release can result in this GI disease
this type of cell is any leukocyte that is NOT a lymphocyte
This is the principle site of extramedullary hematopoiesis
CML and MM share high levels of this purine byproduct
Besides blast crisis, CML can also progress to this disorder, where bone marrow is replaced with scar tissue
extramedullary hematopoiesis in the liver is characteristic of which disease
This disorder can result in a ruddy complexion
the chronic phase of cml lasts for about this many years
PV involves excessive release of this cytokine
This is the most prominent picture of Myeloid metaplasia
Only blast cells are present in this myelogenous disorder
In regards to time, CML and PV are examples of this type of myeloproliferative disorder
MM
In late PV, the bone marrow can become ____________
High rate of cell turnover can produce excessive amounts of this byproduct
in the accelerated phase of cml, there is an increase in this type of immature cell
In CML the transformed pluripotent stem cells predominantly differentiate into this type of cell
This disorder is characterized by a genetic abnormality
A mutation in this tyrosine kinase can lead to PV
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this is the most dominant cell line affected by PV
this acute condition occurs after the accelerated phase in CML patients
This proper noun describes the three thrombolytic properties of PV
This chromosome is present in 90% of patients with CML
In MM, there is malignant proliferation of these platelet forming cells,
For a CML CBC, you can expect markedly increased levels of this cell
This type of PV is a stem cell disorder
in bone marrow, transformation into myelofibrosis marks the beginning of this phase
This component of Virchow's Triad contributes to headache
in this myelogenous disorder, myeloid cells do not spill into the blood
in this disorder, LAP levels are elevated
this clinical disorder describes an abnormally elevated hemoglobin or hematocrit
In this stage of cml, one can find nodular tumors on the skin
Hepatic vein thrombosis is associated with this myeloproliferative disorder`
This is the formation of stacks of RBCs observed in peripheral blood
High Hct/Hb, splenomegaly, and increased RBC mass are major diagnostic criteria of:
These organs are most affected by PV
Look for decreased levels of this enzyme to differentiate cml from infection
Subcapsular infacts of the spleen are a characteristic finding of this disorder

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Created Nov 30, 2010ReportNominate
Tags:disorder