| s | s | s |
| this NRTI should not be taken with tetracycline or fluoroquinolone | |
| NRTI: This analog of deoxythymidine can cause peripheral neuropathy | |
| This disease is the leading cause of infectious mortality in the world | |
| The first T cells to die are those that are specific for fighting _____infection | |
| these inhibitors prevent cleavage of gag pol polyprotein, resulting in immature noninfectious viral particles | |
| zalcitabine should not be given with this NRTI | |
| definition: AIDS wasting | |
| when given with lopinavir, this drug acts as a pharmacologic enhancer | |
| This NRTI should be avoided if the patient is taking didanosine | |
| Known as azt, this is used in preventing vertical transmission of HIV | |
| abacavir associated with this HLA | |
| The window period between infection and seroconversion is about ________ days | |
| The C in ABC stands for | |
| Activation of this immune cell initiates viral replication | |
| Lamivudine should be coadministered with this combo drug | |
| adenosine analog with enteric coating, phenylalanine chewables, take on empty stomach | |
| this NRTI has dose dependent pancreatitis | |
| Long term non progressors have strong production of __________ | |
| This NRTI competes with Stavudine and can cause myelosuppression | |
| entry inhibitor, ccr5 | |
| PI: most potent inhibitor of cyp3a4 | |
| Heterozygosity of this compound imparts protection to AIDS | |
| hyperpigmentation of the palms is a side effect of this drug | |
| | s | s | s |
| This class of drugs does not need phosphorylation and does not compete with nucleoside triphosphate | |
| fusion inhibitor of gp41 | |
| This fluorinated analog of lamivudine can be taken once daily | |
| abacavir can cause this type of reaction | |
| NRTI requires phosphorylation by _______ enzymes | |
| Test: detect antibodies to HIV | |
| This NRTI is used to treat hep B and should be administered with TMP SMZ | |
| This enzyme cleaves viral proteins for viral assembly | |
| This protein product is bound to CD4 and CXCR4 chemokine receptors | |
| These patients have some degree of detectable viremia, but develop hiv about a decade later than normal | |
| toxoplasma, mycobacterium, pneumocystis, and herpes cause this type of infection for aids patients | |
| Test: detect HIV specific proteins | |
| Skin rash is a common result of these two nnrti | |
| fusion entry inhibitors act on these receptors | |
| PI for pregnant women | |
| This area has the most substantial loss of cd4 T cells | |
| integrase inhibitor | |
| emtricitabine's oral solution contains this and is thus contraindicated in pregnant women and children | |
| These HIV seropositive patients never progress to AIDS | |
| Coinfection with this virus promotes cytokines that resist AIDS | |
| An important prognosticator of late stage disease | |
| This nnrti is a moderate inducer of cyp3a4 | |
| During the early stage of HIV infection, this serum measurement is your most important predictor of progressive disease | |
| | s | s | s |
| AZT's highest toxicity | |
| This gene encodes the reverse transcriptase, integrase, and protease | |
| This gene makes the protein of the outer coating of the virus | |
| The major receptor used by HIV to infect T cells | |
| it is important to maintain hydration on an empty stomach with this protease inhibitor | |
| These cells initiate infection by transporting HIV from mucosal surfaces to lymphoid tissue | |
| HIV can lead to a false negative when testing for this disease | |
| Disfiguring major side effect of protease inhibitors | |
| hepatic steatosis and lipid metabolism disorder is an adverse reaction of this class of drugs | |
| delavirdine, efavirenz, and PI's are ______ of cyp enzymes | |
| take this nnrti on an empty stomach, but watch out for CNS toxicity | |
| This type of HIV is found worldwide | |
| env cleaves this to form gp120+gp41 | |
| Acronym: therapy for AIDS | |
| these 3 drugs should be taken on an empty stomach | |
| Protease inhibitors have this suffix | |
| lamivudine is a ______ analog | |
| oral guanosine analog that can cross the bbb | |
| This PI is contraindicated with pts with hepatic failure and sulfa drug allergies | |
| This protease inhibitor can cause hyperbilirubinemia with overt jaundice, increase in qt interval | |
| this class affects p450 and limits its effectiveness and creation | |
| Test: viral load | |
| mucosal ulcers and rash are part of the nonspecific symptoms of __________infection | |
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