Random Science Quiz

Can you name the AIDS Day?

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This disease is the leading cause of infectious mortality in the world
This enzyme cleaves viral proteins for viral assembly
Test: detect antibodies to HIV
this NRTI should not be taken with tetracycline or fluoroquinolone
This class of drugs does not need phosphorylation and does not compete with nucleoside triphosphate
These cells initiate infection by transporting HIV from mucosal surfaces to lymphoid tissue
fusion entry inhibitors act on these receptors
This PI is contraindicated with pts with hepatic failure and sulfa drug allergies
hyperpigmentation of the palms is a side effect of this drug
NRTI requires phosphorylation by _______ enzymes
These patients have some degree of detectable viremia, but develop hiv about a decade later than normal
This nnrti is a moderate inducer of cyp3a4
This NRTI competes with Stavudine and can cause myelosuppression
This gene encodes the reverse transcriptase, integrase, and protease
delavirdine, efavirenz, and PI's are ______ of cyp enzymes
lamivudine is a ______ analog
These HIV seropositive patients never progress to AIDS
Lamivudine should be coadministered with this combo drug
This type of HIV is found worldwide
take this nnrti on an empty stomach, but watch out for CNS toxicity
The C in ABC stands for
Long term non progressors have strong production of __________
This area has the most substantial loss of cd4 T cells
This protease inhibitor can cause hyperbilirubinemia with overt jaundice, increase in qt interval
HIV can lead to a false negative when testing for this disease
toxoplasma, mycobacterium, pneumocystis, and herpes cause this type of infection for aids patients
abacavir can cause this type of reaction
PI: most potent inhibitor of cyp3a4
Coinfection with this virus promotes cytokines that resist AIDS
zalcitabine should not be given with this NRTI
it is important to maintain hydration on an empty stomach with this protease inhibitor
NRTI: This analog of deoxythymidine can cause peripheral neuropathy
The first T cells to die are those that are specific for fighting _____infection
emtricitabine's oral solution contains this and is thus contraindicated in pregnant women and children
hepatic steatosis and lipid metabolism disorder is an adverse reaction of this class of drugs
adenosine analog with enteric coating, phenylalanine chewables, take on empty stomach
Acronym: therapy for AIDS
An important prognosticator of late stage disease
this class affects p450 and limits its effectiveness and creation
entry inhibitor, ccr5
During the early stage of HIV infection, this serum measurement is your most important predictor of progressive disease
abacavir associated with this HLA
Disfiguring major side effect of protease inhibitors
these 3 drugs should be taken on an empty stomach
This NRTI is used to treat hep B and should be administered with TMP SMZ
Protease inhibitors have this suffix
This protein product is bound to CD4 and CXCR4 chemokine receptors
Activation of this immune cell initiates viral replication
PI for pregnant women
mucosal ulcers and rash are part of the nonspecific symptoms of __________infection
when given with lopinavir, this drug acts as a pharmacologic enhancer
This fluorinated analog of lamivudine can be taken once daily
The window period between infection and seroconversion is about ________ days
oral guanosine analog that can cross the bbb
Heterozygosity of this compound imparts protection to AIDS
Test: detect HIV specific proteins
Known as azt, this is used in preventing vertical transmission of HIV
these inhibitors prevent cleavage of gag pol polyprotein, resulting in immature noninfectious viral particles
fusion inhibitor of gp41
This NRTI should be avoided if the patient is taking didanosine
env cleaves this to form gp120+gp41
Skin rash is a common result of these two nnrti
integrase inhibitor
this NRTI has dose dependent pancreatitis
AZT's highest toxicity
Test: viral load
definition: AIDS wasting
The major receptor used by HIV to infect T cells
This gene makes the protein of the outer coating of the virus

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Created Nov 16, 2010ReportNominate