Can you name the drugs in Pharmacology of Infection and Immunity? by RobHampster

Class	Drug	Clue
Lipopeptide		Depolarise membrane
Immunotherapy		Anti ICAM
Beta-lactam (Penicillin)		Broad Spec, Oral Common Penicillin
Painkiller		Common
Oxazolidinone		Works on VRE and MRSA
TB drug		Increase Cell wall perm
DMARD		Peni...
ATS		Grab secreted bile acids - name one
Immunotherapy		Anti IL-6 (begins with T)
Tetracycline		Inhibit tRNA binding on 30s and peptide release
HAART class		Nevirapine, Delavirdine, Efavirenz
Anti Parasitic		block neurotransmitter, administered with Sennosides - Roundworms, Pinworms
Azole/Triazole		Inh. Lanosterol 14a demethylase
DMARD		Old drug. May affect macrophages
Macrolide		Bind 50s blocking pep bond form. Legionella
Anti-inflammatory		Used in Meningitis
New HAART class		Fuzeon
TB drug		FAS1 inh.
Anti fungal		Interferes with tubulin. Old
5-LO inh.		Block LT formation
Beta-lactam (Imipenem)		Broad spectrum of anaerobes and aerobes
Nucleic Acid Inhibitors		Dihydrofolate Reducatase
Affects Eicosanoid Structure		In diet, Fish
NSAID		Anti inflammatory
Cephalosporin 1st Generation		Oral Gram Positive
Anti Parasitic		Block neurone ion channel - Filarial Nematodes
Anti viral drug		Type of Cytokine used to decrease prolif and increase immune resp.
Immunotherapy		Anti IgE (Mast Cell sensitiser Igs)
Nitroimidazole		Anaerobes and Parasites. Affects NA synth.
NSAID		Painkiller & Gastric Side Effects
Beta adrenoceptor agonist		Short Duration
MMP block		Trialled in RA
Arthopod		Name one
		bind Elongation Factor G

Class	Drug	Clue
Immunotherapy		Anti TNF antibody
Immunotherapy		ANti IL1R
Beta-lactamase inhibitor		Sulphur
Cephalosporin 3rd Generation		i.v. Meningitis & G -ve
Quinolone		Last resort quinolone
Quinolone		Inhibit DNA gyrase
Abminister with beta lactams		inhibits dehydropeptidase in renal tubule
DMARD		Inhibit dihydrofolate reductase
Allylamine		Squalene epoxidase inh.
Beta adrenoceptor agonist		Long duration forms depot in membrane and leaks to R
		Broad Spec. binds 50s blocking pep bond form
Chain terminator		most common antiviral, type of NNRRI
Beta adrenoceptor agonist		Long duration diffuses laterally in memb to interact with R
Cell Membrane Disruption		Mycoplasma & Chlamydia
ATS		Class of anti ATS, inh. PPARa and inc. Lipoprot. Lipase
Aminoglycoside		See above begins with Ge
Beta-lactamase inhibitor		Coamoxyclav
Glycopeptide		bind D-Ala-D-Ala
2nd Line TB		Name 1
ATS		Vitamin inh. Liver TG prod. and VLDL secr. also in in tobacco
Rifamycin		TB binds RNA polymerase
Immunotherapy		Anti TNF ab Humanised
Beta-lactam (Penicillin)		First Penicillin
Fungal efflux Inhibitor		Begins Mil
Administer with beta lactams		decrease kidney secretion
Musc. Antagonist		No selective
Nucleic Acid Inhibitors		Dihydropterate Synthetase
Decongestant		Name one
Anti fungal		blocks ^14 reduction & ^7-8 isomerisation
Streptogramins		50s inh. elongation
DMARD		Administrered as a salt. Old drug.
Glycopeptide		bind D-Ala-D-Ala
Anti fungal		RNA & DNA biosynthesis
PDEI		Non selective

Class	Drug	Clue
Immunosuppressant		No grapefruit
Cephalosporin 3rd Generation		i.v. Meningitis & G -ve
Cephalosporin 2nd Generation		i.m. G +ve & G -ve
DMARD		Sounds like a malaria drug
LT inh.		Blocks specific LTs
Immunotherapy		Anti TNF recombinant receptor
Neuraminidase Inh		Name one
Mucolytic		Name one
Beta-lactamase inhibitor		Bromine
TB drug		Mycolic Acid Inhibitor
HAART class		Zidovudine, Didanosine, Zalcitabine, Stavudine, Lamivudine, Abacavir
ATS		Drug class inhibit HMG CoA reductase - name one
Glucocorticoid		Name one
New HAART class		Meraviroc
Anti Parasitic		uncouples Oxidative Phosphorylation - Tapeworms
Adamantanes (M2 inh)		Name one
Cromones		Mast Cell stabilisers
Cell Wall Synth		Prevents D-Ala-D-Ala assembly
Echinocandins		Inh. 1,3b D-glucan synthase
Type4 PDEI		Anti inflammatory
Anti Parasitic		block microtubule assembly and Glu uptake - Tapeworms and Intest. Nematodes
Lincosamide		50s prevent aa forming pep bond
Beta-lactam (Penicillin)		Definition of resistance in MRSA
Beta-lactam (Penicillin)		First Oral Penicillin
Aminoglycoside		Anti TB Ototoxic
Anti fungal		Pokes holes in membrane
Quinolone		Inhibit Topoisomerase 2 - racemic
Anti Parasitic		alters Ca2+ memb. perm. - Flukes, Tapeworms
Musc. Antagonist		M3 selective
Cell Wall Synth		Bactoprenol Inhibitor
HAART class		Saquinavir, Ritonavir,Indinavir, Nelfinavir
Beta-lactam (Monobactam)		i.m. or i.v. for septicaemia or complicated UTI

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