Egg dropped in faeces and mature in soil. they are ingested and hatch in intestine. they penetrate the gut wall and migrate to liver then heart then lung. they grow and are then coughed up and swallowed.10-30cm adult can escape from any orifice though larval migration causes most morbidity.
Caused by trichophyton (mould) often
Short stage in blood then muscle (esp. heart).
Penicillin can cause this in about 5% of people
Tetracyclin forms ROS causing damage
If humans are primary host, no morbidity. Worm just stays in gut. Intermediate host causes morbidity as organism in tissues
Ribavirin used, can be caused by alcohol
Live in subcutaneous tissue and lymphatic tissue. Adults discharge tiny babies which can be ingested by insects. Can cause Elephantiasis and River Blindness.