Susceptible to few drugs, often causes septicaemia. Susceptible to Ceftazidime, Cefoperazone, Cefepime, Cefpirome, Imipenem, Polymixins, Ciprofloxacin
Can be caused by Clindamycin. Killing all susceptible bacteria in gut using a broad spectrum antibiotic can cause...
They multiply in Liver then RBCs. Can cause severe anaemia, haemolysis, pulmonary oedema, metabolic acidosis and hypoglycaemia. Most serious in P. falciparum
Penicillin can cause this in about 5% of people
Can be oral or vaginal. Often treated with oral miconazole.
Often susceptible to vancomycin and linezolid but resistant to Methicillin
Hemaglutinnin, Neuraminidase, ...
Short stage in blood then muscle (esp. heart).
Egg dropped in faeces and mature in soil. they are ingested and hatch in intestine. they penetrate the gut wall and migrate to liver then heart then lung. they grow and are then coughed up and swallowed.10-30cm adult can escape from any orifice though larval migration causes most morbidity.
Neutrophil driven, often causes cyanosis, hypoxia and right heart failure. Mucous is a problem!
Caused by Yeast
Multiplies in blood and CSF disturbing circadian rythms. avoids immune system by using cyclical antigen coats.
Th2 (IL-4,5 & 13) and Eosinophil driven. Hyperresponsiveness
ABCA1 doesn't work so ApoA1 can't pick up cholesterol
S. mansoni, S. haematobium, S. japonicus. Use water snail as intermediate host (can also have secondary host)
Mite burrows into epidermis. Papular eruption.
Often cause gut infection after oral broad spectrum antibiotic
RF present but not Rheumatoid Arthritis. Often features in 'House'
Neutrophilia, no pus, defective fucose metabolism (affects selectins), decreased rolling