Neutrophil driven, often causes cyanosis, hypoxia and right heart failure. Mucous is a problem!
Live in subcutaneous tissue and lymphatic tissue. Adults discharge tiny babies which can be ingested by insects. Can cause Elephantiasis and River Blindness.
Egg dropped in faeces and mature in soil. they are ingested and hatch in intestine. they penetrate the gut wall and migrate to liver then heart then lung. they grow and are then coughed up and swallowed.10-30cm adult can escape from any orifice though larval migration causes most morbidity.
Increases risk of ATS
Caused by trichophyton (mould) often
Recurrent bacterial infections, no pus, Leukocytes don't adhere to endothelium
Ribavirin used, can be caused by alcohol
Itching in Pubic Area
Penicillin can cause this in about 5% of people
Tetracycline often applied topically to cure
Can be oral or vaginal. Often treated with oral miconazole.
They multiply in Liver then RBCs. Can cause severe anaemia, haemolysis, pulmonary oedema, metabolic acidosis and hypoglycaemia. Most serious in P. falciparum
Multiplies in blood and CSF disturbing circadian rythms. avoids immune system by using cyclical antigen coats.
Often cause gut infection after oral broad spectrum antibiotic
RF present but not Rheumatoid Arthritis. Often features in 'House'
Tetracyclin forms ROS causing damage
Cefotaxime/Ceftriaxone often prescribed. Caused by N. meningitidis, H. influenzae, S. pneumoniae, L. monocytogenes, possible C. albicans...
Risk Factor - Bacteria
Co-morbidity with ATS
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