RF present but not Rheumatoid Arthritis. Often features in 'House'
Caused by trichophyton (mould) often
ABCA1 doesn't work so ApoA1 can't pick up cholesterol
They multiply in Liver then RBCs. Can cause severe anaemia, haemolysis, pulmonary oedema, metabolic acidosis and hypoglycaemia. Most serious in P. falciparum
Most common cold causer
Egg dropped in faeces and mature in soil. they are ingested and hatch in intestine. they penetrate the gut wall and migrate to liver then heart then lung. they grow and are then coughed up and swallowed.10-30cm adult can escape from any orifice though larval migration causes most morbidity.
Mite burrows into epidermis. Papular eruption.
Recurrent bacterial infections, no pus, Leukocytes don't adhere to endothelium
Increases risk of ATS
Th2 (IL-4,5 & 13) and Eosinophil driven. Hyperresponsiveness
Can be oral or vaginal. Often treated with oral miconazole.
Tetracyclin forms ROS causing damage
Susceptible to Linezolid but not vancomycin
Neutrophilia, no pus, defective fucose metabolism (affects selectins), decreased rolling
Risk Factor - Bacteria
Co-morbidity with ATS
Short stage in blood then muscle (esp. heart).
Neutrophil driven, often causes cyanosis, hypoxia and right heart failure. Mucous is a problem!
More common where earth is being moved. In lungs.
If humans are primary host, no morbidity. Worm just stays in gut. Intermediate host causes morbidity as organism in tissues
S. mansoni, S. haematobium, S. japonicus. Use water snail as intermediate host (can also have secondary host)