| Significance | Case |
| Congress can make conditional the receipt of federal moneys based on compliance with a federal statute. | |
| Congress can encourage but cannot compel | |
| Struck down Section 3 of the National Industrial Recovery Act. | |
| Congress can suppress a monopoly. Commerce is not a unit. | |
| Mining is not commerce. Upheld E.C. Knight Standard. | |
| Brady Handgun Violence Prevention Act was unconstitutional. Handgun ownership does not affect interstate commerce. | |
| Congress violated the Fifth Amendment when it established the Minimum Wage Board of D.C. | |
| Overruled National League of Cities, Federal Labor Standards Act was constitutional | |