| Function | Amino acid | Additional information |
| Predominant circulating amino acid with the SMALLER molecular mass, used in amino group transport | |
| Immediate precursor of urea in urea cycle | |
| Initial reactant for nonessential amino acid tyrosine's synthesis | |
| Source of second messenger nitric oxide | |
| Important component in the urea cycle, formed in cytoplasm alongside urea in final step | |
| Amino acid neurotransmitter with the LARGER molecular mass - primary excitatory neurotransmitter in the CNS | |
| Yields intermediate in polyamine biosynthesis, which are important for binding to excessive negative charge | |
| Decarboxylated to form histamine | |
| Form of activated ammonium ions, source of ammonium in the kidney | |
| Predominant circulating amino acid with the LARGER molecular mass, used in amino group transport | |
| Source of one-carbon fragments used in biosynthesis | |
| Source of amino groups in transamination reactions | |
| One of the three amino acids involved in creatine biosynthesis | |