| Description | Character | Actor/Actress |
| Main focus of the show,mariage count: 6. One marriage to an english guy, one to a woman in Vegas, one to his best friend, one to a woman with a weight problem, one to some other gi | |
| Mostly comic relief, worked many jobs, complete idiot, nearly married Christa Miller, started out as a DJ, then a Mailman, and finally worked at Neverendingstore.com | |
| Dated hundreds of men throughout the show, married Drew, and finally left in season 8 to marry some guy in 'Nam (i may be istaken on the country). | |
| Drew's arch-enemy, sometimes threw him overboard, ended up being simpatico with him. Had a kid with John Carroll Lynch called 'King Augustus Antonio Carey. | |
| Underrated englishman, Drew's boss for most of the series, also one of his spouse's. Constantly tossed aside and mostly comedic relief. | |
| Drew's childhood friend, housewife, then got divorced, was a stripper, then met Drew again, worked at the warsaw, and had 'Drew Jr' with Drew in the finale. | |
| Drew's brother,used to be a crossdresser,but apparently that dramatic/comedic possible oscar-winning storyline sucked. He also had a kid called 'King Augustus Antonio Carey' with K | |
| Underrated janitor, used mostly for comic relief. He's adopted and a genius apparently. | |
| He's doing the old lady-boss, but ends up with Kathy Kinney, how does she cope? | |
| | Description | Character | Actor/Actress |
| She's comedic relief, and the owner of Winfred-Lauder for a good half of the show. | |
| She goes fat, then thin, leaves Drew. Rinse and repeat. | |
| He's Drew's boss in the last 2 seasons and | |
| The security guard, the only real change you get out of him is that he ends up being Drew's neighbour. | |
| Drew isn't aloud to date her but does anyway, it doesn't last, but he got a dog out of it. | |
| Comic relief, he's the guy that Drew asks for advice, he doesn't give the avice, but they're good scenes. | |
| An old highschool friend of 'the gang' who dates Christa Miller for season 1. | |
| She loses her husband in the final season, and before that she's just what she is, no character development. | |
| He's pretty much comic relief until he falls of Drew's roof and dies in a pink jumpsuit in the final season. | |
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