| Event | Year |
|---|
| The World's first known brandy, Armangac, is distilled. | |
| Byzantine Interregnum period ends, with Mehmet I becoming emperor. | |
| János (John) Hunyadi haults advances of the Turks during the Siege of Belgrade. | |
| Bartholomew Dias reaches Cape of Good Hope. | |
| Leonardo da Vinci is born. | |
| Henry V of England dies. | |
| Ferdinand and Isabella unite Spanish Crown with marriage. | |
| Joan of Arc is believed to be born in this year. | |
| Sigismund becomes Holy Roman Emperor. | |
| The Gutenberg Bible comes is published. | |
| | Event | Year |
|---|
| Vasco da Gama becomes first European India by sea; directly from Europe). | |
| Onin War in Japan begins. | |
| Timur (Tamerlane) dies of the plague (not Black Death.) | |
| Council of Constance begins. | |
| Copernicus is born. | |
| Forbidden Palace begins construction in Peking. | |
| Battle of Shrewsbury takes place. | |
| Treaty of Torsedillas is signed between Portugal and Spain. | |
| Aztec Triple Alliance is established. | |
| Battle of Mortimer's Cross; Henry VI is ousted as King of England. | |
| | Event | Year |
|---|
| University of Leipzig is established. | |
| The Hundred Years' War ends, England loses all but Calais. | |
| Giovanni Caboto (John Cabot) begins his search for the Northwest Passage to China | |
| The Hussite Wars begins. | |
| Vlad Tepes fights off Mehmet II uring The Night Attack | |
| James I of Scotland returns from being a Hostage by English forces. | |
| Pedro Alvarez Cabral is first European to discover Brazil. | |
| Zheng He starts his first of several voyage during the early Ming Dynasty. | |
| Guru Nanak Dev is born. | |
| Matthias Corvinus becomes ruler of Hungary. | |
| | Event | Year |
|---|
| The Pazzi assassination attempt on Lorenzo and Guiliano de Medici (Guiliano dies) | |
| Filippo Brunelleschi dies. | |
| Michelangelo completes Pietà. | |
| Drepung Monestary is founded for teaching of Buddhism. | |
| Eton College is established. | |
| Sonni Ali is first king of the Songhai Empire | |
| The City of Bucharest is founded. | |
| Savonarola is burned at the stake. | |
| Treaty of Troyes is signed between England and France. | |
| Topa Inca Becomes ruler of the Incas. | |
| | Event | Year |
|---|
| Edward V and his younger brother are belived to be murdered in the Tower of London. | |
| Timur (Tamerlane) captures Baghdad. | |
| The Medici bank is established. | |
| The Western Schism officially ends. | |
| Nicholas of Cusa invents concave lenses in order to correct near-sightedness. | |
| The Masjed-e-Kabud (Blue Mosque) is completed | |
| Ivan the III of Russia conquers Tver. | |
| The Empire of Trebizond falls to the Turks, becoming the last of the Byzantine outposts to fall. | |
| The Italian Wars begin. | |
| Zhu Di becomes the Yongle Emperor. | |
|
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