| The first... | Woman | Year |
| Playboy centerfold | |
| to be awarded the Pulitzer Prize for Literature | |
| Australian Prime Minister | |
| Mortal Kombat character | |
| solo host of the Academy Awards | |
elected to Prime Minister of a Muslim state (Pakistan) | |
| to have a global audience of more than 750 million viewers for her wedding AND her funeral | |
to see the resurrected Christ, according to the Gospel of John | |
| former First Lady to be elected to public office | |
| designer to have her name on perfume | |
| Chancellor of Germany | |
pregnant woman to be shown on network television | |
deaf-blind person to earn a Bachelor of Arts degree | |
| to leave the Spice Girls | |
| First Lady (US) | |
| Prime Minister of India | |
| Bond girl in film | |
| Canadian Prime Minister | |
| Protestant Monarch of England | |
| '60 Minutes' correspondent | |
| to run an underground railroad to free slaves | |
| American superstar in marksmanship | |
to become an international movie star at the age of six years old | |
| president of the American Red Cross | |