| Question | Answer |
| Bone cells that degrade bone matrix | |
| Cartilage Zone: large collagen fibers arranged radially on surface, generating cleavage lines | |
| Comp Stress-Strain Mech: Trabecullar bone begins to collapse, acts like'packing foam' | |
| The Intima contains ____ cells and the ____ | |
| In Aneurysms, the radius increases causing the ____ to increase (greek letter) | |
| Endothelial cell response to shear stress: Change in ____ and ____ expression | |
| Cartilage creep test points in order (3) | |
| Cortical bone is 1/3 ______, _____ , and _____ | |
| Endothelial cell response to shear stress: cells ____ in direction of _____ | |
| As the Density Dependence increase there is less ______, while _____, _____, and energy transmission through joints increases | |
| Comp Stress-Strain Mech: Region in which bone absorbs energy until we reach yield stress | |
| The ____ theory models cartilage as a mixture of solid and fluid components which are interdependent | |
| Bone has the ____ Young's Modulus | |
| Cartilage Zone: collagen is mineralized | |
| Cartilage Stress-Strain Mech: the order of degrees to the cleavage line with highest slope to lowest | |
| The superficial zone has collagen fibers, ____, and _____ | |
| Blood Vessels: Stress levels are related to ______ and ____ on endothelial cells | |
| Bone cells that secrete bone matrix | |
| Cartilage is ____ (isotropy) | |
| Tensegrity Model: Tension elments are ____ | |
| Layers of blood vessels from inner to outer | |
| Bone Cells | |
| The middle cylindrical part of the bone is called the _____ region | |
| If mean residual stress is 0, the vessel is in _______ | |
| Keratan sulfate, and chondroitan sulfate are examples of ______- | |
| | Question | Answer |
| In plastic collapse, stress is ___ while strain is ____ | |
| Collagen fibrils are ____ when unloaded | |
| Tensegrity Model: Compression elements are ____ | |
| Loading at higher ____ is more significant than ____ of loading | |
| Cartilage Zone: collagen and proteoglycans | |
| 'sensor molecules' for force transduction; trigger biochemical pathways in cell | |
| Outer layer of bone | |
| Endothelial cell response to shear stress: F- actin bears ____ | |
| Proteoglycans have a strong ____ charge, and bind and attract ____ | |
| Lies on the curved surfaces of joints | |
| Endothelial cell response to shear stress: Increased cell ____ and _____ | |
| Tensegrity Model: Elements | |
| The ______ of the tissue matrix and the ____ of the fluid are dependent on eachother | |
| The loss of articular cartilage with underlying bone degeneration | |
| _____ decreases with age: This is due to an increase in permeability causing a decrease in ____ under load leading to an increase load on the_____ | |
| The media contains ___ cells, and has high ___ content, and moderate ___ content | |
| The equilibrium of cartilage creep test is due to ___ bearing the load | |
| Cells align ______ to stretch direction, this does not occur in ____ conditions | |
| Cortical bone is _____ material: or ______ material defined by orthogonal coordinate system | |
| Cartilage Function: minimal friction | |
| Cartilage is composed of (3) | |
| Spongy, Cancellous bone; 10-50% as dense | |
| Inner layer of bone | |
| Cartilage Function: little deterioration with time | |
| Reduce stress concentrations in joints | |
| | Question | Answer |
| Compact, very dense bone | |
| Cleavage line patterns correspond to ____ created by _____ | |
| Trabecular bone is aligned to bear ______ | |
| Cartilage Zones in order of top to bottom (4) | |
| Cortical bone type: young animals, injury repair | |
| Osteon Lamella are wrapped in ___ fibers to add ductility | |
| The middle zone has collagen fibers and ____ | |
| The adventitia contains _____ as well as elastin and collagen | |
| Comp Stress-Strain Mech: Region in which traceulae have collapsed, stresses begin to rise | |
| Opening angles ___ with increasing pressure | |
| Larger opening angles are attributed to ____ residual stress, while small opening angles are attributed to _____ residual stress | |
| The viscous creep of cartilage creep test is due to ____ | |
| Cartilage Functions (3) | |
| Cartilage Zone: collagen fibers, lubricin, chondrocytes | |
| Endothelial cell response to shear stress: microtubules bear ____ | |
| Cortical bone type consists of parallel osteons 1-2cm in length | |
| 3 Regions of Compressive Strain-Stress Mechanics | |
| Medium sized arteries are known as __ arteries | |
| Density Dependence on bone is characterizied by equation _____ over _____ | |
| Murray's Law of minumum work eventually proves shear stress to be _____ | |
| Large arteries are known as ___ arteries | |
| Blood vessels are located in the _____ of the bone | |
| Cortical bone is 2/3 _______, which mainly _______ | |
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