| Clue | League |
| Only league with no team in Los Angeles: | |
| Only league whose players don't wear helmets: | |
| Only league with no Canadian teams: | |
| Only league never to have a player born in Africa: | |
| Only league never to have had an MVP named 'Joe': | |
| Only league not currently broadcast on ESPN: | |
| Only league with no salary cap: | |
| Only league that doesn't have a holding penalty: | |
| Only league that passes the existing championship trophy on to the next team: | |
| Only league where routine rules infractions require the team to play with fewer players: | |
| Only league where the coaches wear team uniforms: | |
| Only league that measures distances in yards: | |
| Only league that doesn't have a timed clock: | |
| Only league with a single game championship: | |
| Only league never to have a team win 5 or more consecutive championships: | |
| Only league whose championship trophy is not named after a specific person: | |
| Only league whose champion couldn't play for a trophy because of a pandemic: | |
| Only league formed before 1900: | |
| Only league to give out more than one annual (regular season) MVP award: | |
| Only league with an antitrust exemption: | |
| Only league where the object in play isn't made from leather: | |
| Only league in which you can't score any kind of 'goal': | |
| Only league that equally shares all TV revenue amongst the teams: | |
| Only league where teams play more than 100 games per season: | |
| Only league that doesn't have 'league' in its name: | |
| Only league that doesn't use a ball: | |
| Only league whose champion couldn't play for a trophy because of a pandemic: | |
| Only league that doesn't have 'league' in its name: | |
| Only league formed before 1900: | |
| Only league that doesn't have a timed clock: | |
| Only league that doesn't use a ball: | |
| Only league whose players don't wear helmets: | |
| Only league with no Canadian teams: | |
| Only league with no salary cap: | |
| Only league with a single game championship: | |
| Only league in which you can't score any kind of 'goal': | |
| Only league to give out more than one annual (regular season) MVP award: | |
| Only league whose championship trophy is not named after a specific person: | |
| Only league that passes the existing championship trophy on to the next team: | |
| Only league not currently broadcast on ESPN: | |
| Only league that doesn't have a holding penalty: | |
| Only league that measures distances in yards: | |
| Only league where the coaches wear team uniforms: | |
| Only league where the object in play isn't made from leather: | |
| Only league with an antitrust exemption: | |
| Only league that equally shares all TV revenue amongst the teams: | |
| Only league never to have a team win 5 or more consecutive championships: | |
| Only league where teams play more than 100 games per season: | |
| Only league never to have had an MVP named 'Joe': | |
| Only league never to have a player born in Africa: | |
| Only league where routine rules infractions require the team to play with fewer players: | |
| Only league with no team in Los Angeles: | |