| Clue | Answer |
| Site of the first opener outside of the New World | |
| Only player to homer on the first pitch of a major league season | |
| Red Sox pitcher (and future Yankee) who threw a 3 hit shutout against the Yanks on opening day 1917 | |
| Hall of Famer who broke the color barrier on Opening Day 1947 | |
| Dodgers hurler who is the only pitcher to have hit two Opening Day home runs | |
| Network that now broadcasts Sunday night openers | |
| Umpire who tragically collapsed on the field and died on Opening Day in 1996 | |
| NL team that hosted the first night opener | |
| Team that played a record 60 consecutive openers on the road | |
| First 3-time Cy Young Award winner, this Dodger made only one Opening Day start | |
| The NY Giants were forced into Opening Day's only forfeit in 1907 when their fans wouldn't stop throwing these onto the field | |
| Indian who threw the only Opening Day no-hitter | |
| First President to attend an opening day game | |
| Opening Day 1974 saw this man tie Babe Ruth on the all-time HR list | |
| Opening Day 1974 saw this man tie Babe Ruth on the all-time HR list | |
| Opening Day 1974 saw this man tie Babe Ruth on the all-time HR list | |
| Dodgers hurler who is the only pitcher to have hit two Opening Day home runs | |