| Character (Actor/Actress) | Show | Debut |
| Michael Kuzak (Harry Hamlin) | |
| Jean-Luc Picard (Patrick Stewart) | |
| Winnie Cooper (Danica McKellar) | |
| Dr. Sam Beckett (Scott Bakula) | |
| Dale Cooper (Kyle MacLachlan) | |
| Tommy Pickles (E.G. Daily) | |
| Jane Mancini (Josie Bissett) | |
| Dana Scully (Gillian Anderson) | |
| Dr. Douglas Ross (George Clooney) | |
| Gabrielle (Renée O'Connor) | |
| Dick Solomon (John Lithgow) | |
| Xander Harris (Nicholas Brendon) | |
| Samantha Jones (Kim Cattrall) | |
| Philip J. Fry (Billy West) | |
| Larry David (Larry David) | |
| David Fisher (Michael C. Hall) | |
| Malcolm Reynolds (Nathan Fillion) | |
| Sean McNamara (Dylan Walsh) | |
| Susan Mayer (Teri Hatcher) | |
| Ted Mosby (Josh Radnor) | |
| Hiro Nakamura (Masi Oka) | |
| Don Draper (Jon Hamm) | |
| Sookie Stackhouse (Anna Paquin) | |
| Elena Gilbert (Nina Dobrev) | |
| Nucky Thompson (Steve Buscemi) | |