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BDS Year 2 Drugs
Can you pick the drugs that came up in ebl this year?
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a corticosteroid used to treat asthma - taken every day via inhaler to prevent inflammation
a beta-2 adrenoceptor agonist used to treat asthma - take as needed via inhaler to dilate bronchioles
inhibits bacterial/fungal folic acid synthesis, used to treat PCP (pneumocystic jirovecii pneumonia)
An over-the-counter analgesic and antipyretic, extensively metabolised in the liver by P450 enzymes. A small fraction forms NAPBQI which is hepatotoxic in absence of glutathione
Analgesic, antipyretic, anti-platelet NSAID. irreversibly inhibits COX [arachidonic acid -> prostaglandin H2] before deacetylated in plasma to salicylic acid
Analgesic, antipyretic, and mild anti-platelet NSAID derived from propionic acid. Comes as a racemate; the S-enantiomer inhibits COX and the R form is converted to S
A potent analgesic for severe pain; acts on opoid receptors to inhibit release of nociceptive neurotransmitters eg. substance P and GABA
Used to treat angina, administered parentally (sublingual/transdermal), it is converted to NO (vasodilator)
A selective beta-1 receptor antagonist (beta blocker) used to treat cardiovascular disease by reducing cardiac contractility and blood pressure
A loop diuretic used to treat hypertension. Inhibits the Na-K-2Cl symporter in the thick ascending limb of loop of Henle
A thiazaide diuretic which inhibits Na+ absorption in the DCT
Most prescribed drug in UK. Treats hypercholesterolemia by competitively inhibiting HMG-CoA reductase
An ACE-inhibitor which is the 4th top prescribed drug in the UK. Used to treat high blood pressure by inhibiting formation of Angiotensin II
a proton pump inhibitor used in the treatment of dyspepsia, peptic ulcer, and GORD. Inhibits gastric acid secretion by inhibiting H-K-ATPase
a compound analgesic for management of moderate pain and as a cough suppressant. Consists of a combination of an opioid analgesic and an over-the-counter analgesic/antipyretic.
for atrial arrthymias, steroid-like, derived from foxgloves, increase cardiac contractility and reduces heart rate
for pulmonary embolism and unstable angina, given parentally, and acts by helping the enzyme antithrombin III to inhibit thrombin and factor X
an oral anticoagulant prescribed long-term for those at risk of DVT or with artificial heart valves etc. Inhibits epoxide reductase diminishing availability of vitamin K
the biggest-selling HIV drug worldwide - ‘one pill a day’, contains 2 NRTIs and an NNRTI (non-nucleoside reverse transcriptase inhibitor)
stimulates foetal haemoglobin production in the treatment of sickle cell anaemia
A protein from streptococci bacteria. Acts to dissolve thrombus in pulm emb/MI by activating plasminogen to plasmin which then dissolves fibrin
an amino-amide anaesthetic agent and cardiac depressant. It binds to and blocks the voltage gated Na+ channels in neuronal cell membranes
a non-setting intra-canal medicament containing triamcinolone (an anti-inflammatory, anti-osteoclast steroid) and demeclocycline (a tetracycline antibiotic). No need to mix before
a hard-setting material for use on dentine as a lining, as a pulp capping agent, or as a pulpotomy agent. Comes as a powder and liquid to mix
beta-lactam antibiotic primarily for gram-positive, susceptible bacteria eg streptococcus. inhibits cell wall synthesis
Antibiotic primarily active against anaerobic bacteria - inhibits critical enzymes within the bacterium
Antifungal agent applied topically. Inhibits synthesis of ergosterol, found in fungal cell membranes. Used against Candida but NOT with warfarin
Antifungal agent, inhibits synthesis of ergosterol, may be taken with warfarin
A class of drugs used in osteoporosis treatment, which bind to hydroxyapatite and inhibit osteoclast action
An opoid prescribed to drug abuse recoverers; inhibits saliva production and can lead to rampant caries
'Laughing gas', a slightly sweet tasting/smelling gas with analgesic (opoid) and anti-anxiety properties
A drug for cancer, rheumatoid arthritis, and to induce abortion. binds to the most rapidly diving cells. possible t-cell suppression mechanism against RA
Epilepsy drug associated with gingival enlargement
An essential mineral for Hb formation. RDA: 9mg for men, 15mg women, but only 5-10% is absorbed (upper GI). Liver, meat, beans, nuts, curly kale and dried apricots
For RBC nuclear maturation. Meat, salmon, milk, and eggs. Needs intrinsic factor for absorption
For Hb formation. Also known as pyridoxine. Pork, chicken, veg, peanuts, potatoes
For RBC nuclear maturation. Supplements taken in preganancy to avoid baby's CNS problems. Broccoli, sprouts, spinach, asparagus
Increases calcium ion concentration in the blood. Non-essential vitamin partic in summer. Salmon, mackerel, eggs.
Aka ascorbic acid. Needed for connective tissue. (perio disease!) Strawberries, oranges, red peppers, blackberries, broccoli
For bones, teeth, and muscle contraction. RDA: 700mg. Milk, cheese, yoghurt, soya, broccoli, cabbage
A fat soluble vit made in plants for photosynthesis. Required for clotting factors II (thrombin), VII, IX, X and proteins C and S. Broccoli, sprouts, spinach.
A non-selective Beta 1 and beta 2 receptor antagonist used to treat hypertension
A short acting benzodiazepine used intravenously in adult patients requiring conscious sedation, diminishes anxiety, relaxes muscles and induces amnesia
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