| Played | Actor | Also Known For |
| Himself | |
| Milton Greene | |
| Himself | |
| Himself | |
| Claire Harper | |
| Raheem Haddad | |
| Devon Banks | |
| Avery Jessup | |
| Herself | |
| Brad Halster | |
| Herself | |
| Himself | |
| Himself | |
| Steven Black | |
| Herself | |
| Cooter Burger | |
| Lenny Wosniak | |
| Himself | |
| Himself | |
| Himself | |
| Bucky Bright | |
| Himself | |
| Herself | |
| Himself | |
| Carol | |
| Mickey J | |
| Stewart | |
| Several Characters | |
| Rick Wayne | |
| Himself | |
| Rosemary Howard | |
| Himself | |
| Shane Hunter | |
| Rosemary Howard | |
| Tomas; Paul | |
| Himself | |
| Herself | |
| Herself | |
| | Played | Actor | Also Known For |
| Himself | |
| Himself | |
| Dr. Drew Baird | |
| Himself | |
| Elisa | |
| Jesse Parcell | |
| Dick Lemon | |
| Walter | |
| Himself | |
| Verna Maroney | |
| Himself | |
| Ridikolus | |
| Danny Baker | |
| Himself | |
| Herself | |
| Himself | |
| Himself | |
| Himself | |
| Herself | |
| Himself | |
| Herself | |
| Herself | |
| Eddie Donaghy | |
| Himself | |
| Herself | |
| Himself | |
| Himself | |
| Sylvia Rossitano | |
| Gretchen Thomas | |
| Gavin Volure | |
| Himself | |
| Himself | |
| Himself | |
| Himself | |
| Himself | |
| Himself | |
| Nancy Donovan | |
| Phoebe | |
| | Played | Actor | Also Known For |
| Bev | |
| Asif | |
| Erin O'Neal | |
| Himself | |
| Herself | |
| Sportscaster | |
| Sid | |
| Dr. Leo Spaceman | |
| Herself | |
| Himself | |
| Himself | |
| Dr. Kaplan | |
| Gerhardt | |
| Mitch Lemon | |
| Himself | |
| Himself | |
| Bianca Donaghy | |
| Maynard | |
| Greenzo/ Jared | |
| Himself | |
| Katherine Catherine Donaghy | |
| Wesley Snipes | |
| Angie Jordan | |
| Colleen Donaghy | |
| Floyd | |
| Tracy Jordan Jr. | |
| Don Geiss | |
| Herself | |
| Himself | |
| Himself | |
| Herself | |
| Candace Van der Shark | |
| Himself | |
| Herself | |
| Dennis Duffy | |
| Herself | |
| Himself (voice) | |
| Himself (voice) | |
| Himself (voice) | |
|