| Clue | Answer | Year |
|---|
| He threw the only no-hitter in Opening Day history. | |
| He was the first president to throw the out the first pitch on Opening Day. | |
| The longest Opening Day game between the Detroit Tigers and the Cleveland Indians lasted this many innings. | |
| The first Opening Day doubleheader was between the Philadelphia Athletics and this team. | |
| He holds the record for starting in the most Opening Day games, 16. | |
| He was the first to hit a home run out of Yankee Stadium in history on Opening Day. | |
| Sixto Lezcano is the only player in history to hit two of these on Opening Days. | |
| This player toppled the color barrier in baseball when he helped the Dodgers beat the Braves on Opening Day. | |
| This team won the first Opening Day on foreign soil when they beat the Padres in Monterrey's Estadio de Beisbol. | |
| Opening Day between the New York Giants and Philadelphia Phillies ended in forfeit when annoyed fans threw these onto the field. | |
MLB Teams 
NBA Teams 
Division-I Basketball
