| Description | Cause |
| The states formed an agreement | |
| South Carolina's attempt to veto a federal tariff | |
| Novel that pushed neutrals to abolitionism | |
| Repealed the Missouri Compromise | |
| Radical attempt to free slaves at Harper's Ferry | |
| Stricter rules for slaves after Nat Turner's rebellion | |
| Missourians crossed over state lines to vote for slavery | |
| Stephen Douglas' proposition for popular sovereignty | |
| | Description | Cause |
| Abolished slave trade in D.C | |
| Proposed no slavery in new Mexican territories | |
| Uprising that sparked fear of slave's revolts in South | |
| Elected president who was disliked by Southerners | |
| Fort attacked by South Carolina that started the Civil War | |
| Act that formed the Confederacy | |
| Senator beaten for remarks about nullification | |
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