Infectious Disease Block 6 - Fungus

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Can you name the Infectious Disease Block 6?

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Tx for Zygomycetes
Risk factor for yeast infection
Never use this for diagnosis of cryptococcus
Anti-fungal with 3 fluorides. Tx for aspergillus. S/E - Bone pain, alteration in electroretinogram, increased alkaline phos, periostitis, Visual scatoma. Multiple drug interactions
Arizona/mexico border, Confussion/meningitis
Drug that is concentrated in the skin. Side effect is a loss of taste. Effective against dimorphic fungi in nails and skin
Bone fungal infections
Drug with multiple double bonds and intercalates into fungal plasma membranes creating lytic pores
diaper rash
Need to suppliment with potassium, magnesium and EPO because of its renal toxicity.
Parental drug addict mucormycosis
candida strain resistant to azoles
Dx stain for Cryto
DNA synthesis inhibitor. Goes to the CNS. Can Cause hemorrhagic colitis and pancytopenia
Athletes foot
Pseudo membrane in oropharynx - thrush.
Side effects are: Shake and Bake (fever chills, headache, nausea, vomiting) mediated through release of prostaglandin E. Renal toxicity is closely watched.
Bind to fungal heme iron in cytochrome P-450
Ubiquitous with hyphae branching at acute angles
Drug addict, diabetic w/ ketoacidosis, Bone transplant recipient, Renal Failure. Black necrosis of the ororpharynx. Rapid presentation
Fungal infection causing baldness
Low Alkaline phosphatase, LDH less than 300, Leukocytopenia. Diagnosed via urine serology
Broad base budding, In soil. Great lakes. Beavers. Hits Normal immune systems. Fisherman, campers, hunters
prophylaxis for pneumocystis and toxoplasmosis
Skinny white male with COPD gets this fungal infection. pneumoia pericarditis, adrenal disease, adenocarcinoma like bowel lesions
Rapid O2 desaturation upon exertion. Life threatening pneumonia in AIDS. Ubiquitous
Diabetic mucormycosis
Jock Rot 'well demarcated line'
QuestionAnswerAdditional information
Anti-fungal with Side effects of adrenal Insufficiency and hepatic necrosis. Needs gastric acid for absorption
Intracellular fungus, Spelunking, prisons, chicken coops
Massive laryngeal mass causing obstruction - South americam agricultural worker
Fungal infection that runs along lymphatic vessel. Rose growers disease
Serology is great and should ALWAYS be followed
Verrucous/warty skin lesions in cooler areas (tip of nose, fingers)
right angle hyphae
Antifungal drug whose mechanism is similar to that of penicillin to bacteria. Tx for candida and aspergillus.
When in serum grows pseudohyphae. Retinal presentations
Distal finger nail infection
MCC of fungal meningitis in AIDS pts. Pidgeon poop.
Immunecompromised w/ old dressings or IVs mucormycosis
Strain of cryptococcus that hits immunecompromised
Strain of cryptococcus on the west coast and hits non-immuncompromised
Dose dependent Candida strain
Serology is terrible and is often false positive for histoplasmosis
Tx for cryptococcus meningitis (Abv.)
Apical lung fungal ball
HIV, Thailand, Red pigment
Narrow base budding
erythema nodosum, hilar adenopathy. Apical cavitary disease. Dark skin and pregnancy are risk factors. Meningitis = Tx for life
Tx for histoplasmosis, spirotrichosis, and blastomyces. Taken with food/coca cola. Side effects: Adrenal excess (edema, hypertension, hypokalemia) nausea, vomiting. Long term - per
HIV Finger nail infection
Treats ring worm and nail infections. Inhibits nucleic acid synthesis
Ring worm
Halo sign, wedge shaped pulmonary emboli infarct, immune compromised
Antifungal to treat fungal UTI's and has CSF penetration. Great pharmacokinetics.Treats coccidioides.
Bone marrow recipients/leukemic pts. mucormycosis

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