Science / Infectious Disease Block 6 - Fungus

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Can you name the Infectious Disease Block 6?

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QuestionAnswerAdditional information
diaper rash
Massive laryngeal mass causing obstruction - South americam agricultural worker
Skinny white male with COPD gets this fungal infection. pneumoia pericarditis, adrenal disease, adenocarcinoma like bowel lesions
Tx for cryptococcus meningitis (Abv.)
Diabetic mucormycosis
Broad base budding, In soil. Great lakes. Beavers. Hits Normal immune systems. Fisherman, campers, hunters
Bind to fungal heme iron in cytochrome P-450
Halo sign, wedge shaped pulmonary emboli infarct, immune compromised
Never use this for diagnosis of cryptococcus
Drug with multiple double bonds and intercalates into fungal plasma membranes creating lytic pores
Risk factor for yeast infection
Parental drug addict mucormycosis
erythema nodosum, hilar adenopathy. Apical cavitary disease. Dark skin and pregnancy are risk factors. Meningitis = Tx for life
Jock Rot 'well demarcated line'
Intracellular fungus, Spelunking, prisons, chicken coops
prophylaxis for pneumocystis and toxoplasmosis
Distal finger nail infection
Bone fungal infections
Fungal infection that runs along lymphatic vessel. Rose growers disease
Dose dependent Candida strain
Need to suppliment with potassium, magnesium and EPO because of its renal toxicity.
Drug addict, diabetic w/ ketoacidosis, Bone transplant recipient, Renal Failure. Black necrosis of the ororpharynx. Rapid presentation
Serology is great and should ALWAYS be followed
Athletes foot
Side effects are: Shake and Bake (fever chills, headache, nausea, vomiting) mediated through release of prostaglandin E. Renal toxicity is closely watched.
right angle hyphae
Treats ring worm and nail infections. Inhibits nucleic acid synthesis
Verrucous/warty skin lesions in cooler areas (tip of nose, fingers)
QuestionAnswerAdditional information
Antifungal drug whose mechanism is similar to that of penicillin to bacteria. Tx for candida and aspergillus.
Apical lung fungal ball
Pseudo membrane in oropharynx - thrush.
Bone marrow recipients/leukemic pts. mucormycosis
When in serum grows pseudohyphae. Retinal presentations
Strain of cryptococcus that hits immunecompromised
Immunecompromised w/ old dressings or IVs mucormycosis
Anti-fungal with 3 fluorides. Tx for aspergillus. S/E - Bone pain, alteration in electroretinogram, increased alkaline phos, periostitis, Visual scatoma. Multiple drug interactions
Dx stain for Cryto
HIV, Thailand, Red pigment
Antifungal to treat fungal UTI's and has CSF penetration. Great pharmacokinetics.Treats coccidioides.
Ubiquitous with hyphae branching at acute angles
Narrow base budding
Low Alkaline phosphatase, LDH less than 300, Leukocytopenia. Diagnosed via urine serology
Arizona/mexico border, Confussion/meningitis
candida strain resistant to azoles
Anti-fungal with Side effects of adrenal Insufficiency and hepatic necrosis. Needs gastric acid for absorption
Serology is terrible and is often false positive for histoplasmosis
Fungal infection causing baldness
Rapid O2 desaturation upon exertion. Life threatening pneumonia in AIDS. Ubiquitous
Tx for histoplasmosis, spirotrichosis, and blastomyces. Taken with food/coca cola. Side effects: Adrenal excess (edema, hypertension, hypokalemia) nausea, vomiting. Long term - per
Drug that is concentrated in the skin. Side effect is a loss of taste. Effective against dimorphic fungi in nails and skin
DNA synthesis inhibitor. Goes to the CNS. Can Cause hemorrhagic colitis and pancytopenia
Tx for Zygomycetes
Strain of cryptococcus on the west coast and hits non-immuncompromised
HIV Finger nail infection
MCC of fungal meningitis in AIDS pts. Pidgeon poop.
Ring worm

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