Infectious Disease Block 6 - Fungus

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Can you name the Infectious Disease Block 6?

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QuestionAnswerAdditional information
Broad base budding, In soil. Great lakes. Beavers. Hits Normal immune systems. Fisherman, campers, hunters
When in serum grows pseudohyphae. Retinal presentations
Strain of cryptococcus that hits immunecompromised
Immunecompromised w/ old dressings or IVs mucormycosis
Anti-fungal with 3 fluorides. Tx for aspergillus. S/E - Bone pain, alteration in electroretinogram, increased alkaline phos, periostitis, Visual scatoma. Multiple drug interactions
Diabetic mucormycosis
Dx stain for Cryto
Skinny white male with COPD gets this fungal infection. pneumoia pericarditis, adrenal disease, adenocarcinoma like bowel lesions
HIV Finger nail infection
prophylaxis for pneumocystis and toxoplasmosis
Intracellular fungus, Spelunking, prisons, chicken coops
Serology is great and should ALWAYS be followed
Anti-fungal with Side effects of adrenal Insufficiency and hepatic necrosis. Needs gastric acid for absorption
diaper rash
Jock Rot 'well demarcated line'
Massive laryngeal mass causing obstruction - South americam agricultural worker
Rapid O2 desaturation upon exertion. Life threatening pneumonia in AIDS. Ubiquitous
Low Alkaline phosphatase, LDH less than 300, Leukocytopenia. Diagnosed via urine serology
erythema nodosum, hilar adenopathy. Apical cavitary disease. Dark skin and pregnancy are risk factors. Meningitis = Tx for life
Athletes foot
HIV, Thailand, Red pigment
Side effects are: Shake and Bake (fever chills, headache, nausea, vomiting) mediated through release of prostaglandin E. Renal toxicity is closely watched.
Bone fungal infections
Verrucous/warty skin lesions in cooler areas (tip of nose, fingers)
Tx for histoplasmosis, spirotrichosis, and blastomyces. Taken with food/coca cola. Side effects: Adrenal excess (edema, hypertension, hypokalemia) nausea, vomiting. Long term - per
Narrow base budding
Drug that is concentrated in the skin. Side effect is a loss of taste. Effective against dimorphic fungi in nails and skin
Ring worm
QuestionAnswerAdditional information
Risk factor for yeast infection
Dose dependent Candida strain
candida strain resistant to azoles
Apical lung fungal ball
Serology is terrible and is often false positive for histoplasmosis
DNA synthesis inhibitor. Goes to the CNS. Can Cause hemorrhagic colitis and pancytopenia
Tx for cryptococcus meningitis (Abv.)
Tx for Zygomycetes
Arizona/mexico border, Confussion/meningitis
Drug with multiple double bonds and intercalates into fungal plasma membranes creating lytic pores
Drug addict, diabetic w/ ketoacidosis, Bone transplant recipient, Renal Failure. Black necrosis of the ororpharynx. Rapid presentation
Treats ring worm and nail infections. Inhibits nucleic acid synthesis
Antifungal to treat fungal UTI's and has CSF penetration. Great pharmacokinetics.Treats coccidioides.
Distal finger nail infection
Need to suppliment with potassium, magnesium and EPO because of its renal toxicity.
Fungal infection causing baldness
Bind to fungal heme iron in cytochrome P-450
Never use this for diagnosis of cryptococcus
Halo sign, wedge shaped pulmonary emboli infarct, immune compromised
Pseudo membrane in oropharynx - thrush.
MCC of fungal meningitis in AIDS pts. Pidgeon poop.
Ubiquitous with hyphae branching at acute angles
right angle hyphae
Strain of cryptococcus on the west coast and hits non-immuncompromised
Fungal infection that runs along lymphatic vessel. Rose growers disease
Parental drug addict mucormycosis
Antifungal drug whose mechanism is similar to that of penicillin to bacteria. Tx for candida and aspergillus.
Bone marrow recipients/leukemic pts. mucormycosis

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