Infectious Disease Block 6 - Fungus

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Can you name the Infectious Disease Block 6?

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QuestionAnswerAdditional information
Bone marrow recipients/leukemic pts. mucormycosis
Fungal infection causing baldness
Pseudo membrane in oropharynx - thrush.
Parental drug addict mucormycosis
Strain of cryptococcus on the west coast and hits non-immuncompromised
Massive laryngeal mass causing obstruction - South americam agricultural worker
Fungal infection that runs along lymphatic vessel. Rose growers disease
Dx stain for Cryto
DNA synthesis inhibitor. Goes to the CNS. Can Cause hemorrhagic colitis and pancytopenia
Ubiquitous with hyphae branching at acute angles
MCC of fungal meningitis in AIDS pts. Pidgeon poop.
Drug addict, diabetic w/ ketoacidosis, Bone transplant recipient, Renal Failure. Black necrosis of the ororpharynx. Rapid presentation
Antifungal drug whose mechanism is similar to that of penicillin to bacteria. Tx for candida and aspergillus.
Distal finger nail infection
Tx for histoplasmosis, spirotrichosis, and blastomyces. Taken with food/coca cola. Side effects: Adrenal excess (edema, hypertension, hypokalemia) nausea, vomiting. Long term - per
When in serum grows pseudohyphae. Retinal presentations
Athletes foot
Dose dependent Candida strain
erythema nodosum, hilar adenopathy. Apical cavitary disease. Dark skin and pregnancy are risk factors. Meningitis = Tx for life
Immunecompromised w/ old dressings or IVs mucormycosis
Halo sign, wedge shaped pulmonary emboli infarct, immune compromised
Narrow base budding
Tx for Zygomycetes
Serology is great and should ALWAYS be followed
Treats ring worm and nail infections. Inhibits nucleic acid synthesis
Bind to fungal heme iron in cytochrome P-450
diaper rash
Ring worm
QuestionAnswerAdditional information
Risk factor for yeast infection
Skinny white male with COPD gets this fungal infection. pneumoia pericarditis, adrenal disease, adenocarcinoma like bowel lesions
Serology is terrible and is often false positive for histoplasmosis
HIV, Thailand, Red pigment
Anti-fungal with 3 fluorides. Tx for aspergillus. S/E - Bone pain, alteration in electroretinogram, increased alkaline phos, periostitis, Visual scatoma. Multiple drug interactions
Never use this for diagnosis of cryptococcus
Apical lung fungal ball
Intracellular fungus, Spelunking, prisons, chicken coops
Rapid O2 desaturation upon exertion. Life threatening pneumonia in AIDS. Ubiquitous
Jock Rot 'well demarcated line'
candida strain resistant to azoles
HIV Finger nail infection
Anti-fungal with Side effects of adrenal Insufficiency and hepatic necrosis. Needs gastric acid for absorption
Antifungal to treat fungal UTI's and has CSF penetration. Great pharmacokinetics.Treats coccidioides.
Arizona/mexico border, Confussion/meningitis
Tx for cryptococcus meningitis (Abv.)
prophylaxis for pneumocystis and toxoplasmosis
Drug with multiple double bonds and intercalates into fungal plasma membranes creating lytic pores
Low Alkaline phosphatase, LDH less than 300, Leukocytopenia. Diagnosed via urine serology
Drug that is concentrated in the skin. Side effect is a loss of taste. Effective against dimorphic fungi in nails and skin
Broad base budding, In soil. Great lakes. Beavers. Hits Normal immune systems. Fisherman, campers, hunters
Side effects are: Shake and Bake (fever chills, headache, nausea, vomiting) mediated through release of prostaglandin E. Renal toxicity is closely watched.
Strain of cryptococcus that hits immunecompromised
Diabetic mucormycosis
right angle hyphae
Verrucous/warty skin lesions in cooler areas (tip of nose, fingers)
Need to suppliment with potassium, magnesium and EPO because of its renal toxicity.
Bone fungal infections

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