Science / Infectious Disease Block 6 - Fungus

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Can you name the Infectious Disease Block 6?

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QuestionAnswerAdditional information
When in serum grows pseudohyphae. Retinal presentations
Need to suppliment with potassium, magnesium and EPO because of its renal toxicity.
Ubiquitous with hyphae branching at acute angles
MCC of fungal meningitis in AIDS pts. Pidgeon poop.
Treats ring worm and nail infections. Inhibits nucleic acid synthesis
Strain of cryptococcus on the west coast and hits non-immuncompromised
Low Alkaline phosphatase, LDH less than 300, Leukocytopenia. Diagnosed via urine serology
Fungal infection that runs along lymphatic vessel. Rose growers disease
Diabetic mucormycosis
right angle hyphae
Broad base budding, In soil. Great lakes. Beavers. Hits Normal immune systems. Fisherman, campers, hunters
Risk factor for yeast infection
Narrow base budding
HIV Finger nail infection
Fungal infection causing baldness
Bind to fungal heme iron in cytochrome P-450
Dose dependent Candida strain
Serology is terrible and is often false positive for histoplasmosis
Drug addict, diabetic w/ ketoacidosis, Bone transplant recipient, Renal Failure. Black necrosis of the ororpharynx. Rapid presentation
Antifungal to treat fungal UTI's and has CSF penetration. Great pharmacokinetics.Treats coccidioides.
Skinny white male with COPD gets this fungal infection. pneumoia pericarditis, adrenal disease, adenocarcinoma like bowel lesions
candida strain resistant to azoles
Athletes foot
Drug that is concentrated in the skin. Side effect is a loss of taste. Effective against dimorphic fungi in nails and skin
Ring worm
Immunecompromised w/ old dressings or IVs mucormycosis
Side effects are: Shake and Bake (fever chills, headache, nausea, vomiting) mediated through release of prostaglandin E. Renal toxicity is closely watched.
Halo sign, wedge shaped pulmonary emboli infarct, immune compromised
QuestionAnswerAdditional information
Dx stain for Cryto
DNA synthesis inhibitor. Goes to the CNS. Can Cause hemorrhagic colitis and pancytopenia
prophylaxis for pneumocystis and toxoplasmosis
Arizona/mexico border, Confussion/meningitis
Antifungal drug whose mechanism is similar to that of penicillin to bacteria. Tx for candida and aspergillus.
Tx for cryptococcus meningitis (Abv.)
erythema nodosum, hilar adenopathy. Apical cavitary disease. Dark skin and pregnancy are risk factors. Meningitis = Tx for life
Anti-fungal with Side effects of adrenal Insufficiency and hepatic necrosis. Needs gastric acid for absorption
Apical lung fungal ball
Parental drug addict mucormycosis
diaper rash
Anti-fungal with 3 fluorides. Tx for aspergillus. S/E - Bone pain, alteration in electroretinogram, increased alkaline phos, periostitis, Visual scatoma. Multiple drug interactions
Bone fungal infections
HIV, Thailand, Red pigment
Serology is great and should ALWAYS be followed
Strain of cryptococcus that hits immunecompromised
Tx for histoplasmosis, spirotrichosis, and blastomyces. Taken with food/coca cola. Side effects: Adrenal excess (edema, hypertension, hypokalemia) nausea, vomiting. Long term - per
Pseudo membrane in oropharynx - thrush.
Jock Rot 'well demarcated line'
Drug with multiple double bonds and intercalates into fungal plasma membranes creating lytic pores
Never use this for diagnosis of cryptococcus
Tx for Zygomycetes
Massive laryngeal mass causing obstruction - South americam agricultural worker
Intracellular fungus, Spelunking, prisons, chicken coops
Bone marrow recipients/leukemic pts. mucormycosis
Verrucous/warty skin lesions in cooler areas (tip of nose, fingers)
Distal finger nail infection
Rapid O2 desaturation upon exertion. Life threatening pneumonia in AIDS. Ubiquitous

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