Infectious Disease Block 6 - Fungus

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QuestionAnswerAdditional information
Anti-fungal with Side effects of adrenal Insufficiency and hepatic necrosis. Needs gastric acid for absorption
Side effects are: Shake and Bake (fever chills, headache, nausea, vomiting) mediated through release of prostaglandin E. Renal toxicity is closely watched.
Halo sign, wedge shaped pulmonary emboli infarct, immune compromised
Jock Rot 'well demarcated line'
Drug that is concentrated in the skin. Side effect is a loss of taste. Effective against dimorphic fungi in nails and skin
Dx stain for Cryto
Need to suppliment with potassium, magnesium and EPO because of its renal toxicity.
Risk factor for yeast infection
Ubiquitous with hyphae branching at acute angles
Rapid O2 desaturation upon exertion. Life threatening pneumonia in AIDS. Ubiquitous
HIV, Thailand, Red pigment
Massive laryngeal mass causing obstruction - South americam agricultural worker
Drug with multiple double bonds and intercalates into fungal plasma membranes creating lytic pores
When in serum grows pseudohyphae. Retinal presentations
Strain of cryptococcus on the west coast and hits non-immuncompromised
MCC of fungal meningitis in AIDS pts. Pidgeon poop.
Serology is great and should ALWAYS be followed
Antifungal drug whose mechanism is similar to that of penicillin to bacteria. Tx for candida and aspergillus.
Fungal infection causing baldness
Fungal infection that runs along lymphatic vessel. Rose growers disease
Never use this for diagnosis of cryptococcus
right angle hyphae
Treats ring worm and nail infections. Inhibits nucleic acid synthesis
erythema nodosum, hilar adenopathy. Apical cavitary disease. Dark skin and pregnancy are risk factors. Meningitis = Tx for life
Serology is terrible and is often false positive for histoplasmosis
Skinny white male with COPD gets this fungal infection. pneumoia pericarditis, adrenal disease, adenocarcinoma like bowel lesions
prophylaxis for pneumocystis and toxoplasmosis
Broad base budding, In soil. Great lakes. Beavers. Hits Normal immune systems. Fisherman, campers, hunters
QuestionAnswerAdditional information
Dose dependent Candida strain
Intracellular fungus, Spelunking, prisons, chicken coops
Ring worm
Bind to fungal heme iron in cytochrome P-450
Immunecompromised w/ old dressings or IVs mucormycosis
Anti-fungal with 3 fluorides. Tx for aspergillus. S/E - Bone pain, alteration in electroretinogram, increased alkaline phos, periostitis, Visual scatoma. Multiple drug interactions
Tx for Zygomycetes
Arizona/mexico border, Confussion/meningitis
Antifungal to treat fungal UTI's and has CSF penetration. Great pharmacokinetics.Treats coccidioides.
Distal finger nail infection
Apical lung fungal ball
Diabetic mucormycosis
Tx for cryptococcus meningitis (Abv.)
Narrow base budding
Tx for histoplasmosis, spirotrichosis, and blastomyces. Taken with food/coca cola. Side effects: Adrenal excess (edema, hypertension, hypokalemia) nausea, vomiting. Long term - per
Bone fungal infections
Athletes foot
HIV Finger nail infection
Pseudo membrane in oropharynx - thrush.
Bone marrow recipients/leukemic pts. mucormycosis
candida strain resistant to azoles
diaper rash
Verrucous/warty skin lesions in cooler areas (tip of nose, fingers)
Strain of cryptococcus that hits immunecompromised
DNA synthesis inhibitor. Goes to the CNS. Can Cause hemorrhagic colitis and pancytopenia
Drug addict, diabetic w/ ketoacidosis, Bone transplant recipient, Renal Failure. Black necrosis of the ororpharynx. Rapid presentation
Parental drug addict mucormycosis
Low Alkaline phosphatase, LDH less than 300, Leukocytopenia. Diagnosed via urine serology

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Created Jun 23, 2012ReportNominate
Tags:block, disease, fungus, infection