Infectious Disease Block 6 - Fungus

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Can you name the Infectious Disease Block 6?

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Tx for cryptococcus meningitis (Abv.)
erythema nodosum, hilar adenopathy. Apical cavitary disease. Dark skin and pregnancy are risk factors. Meningitis = Tx for life
Antifungal to treat fungal UTI's and has CSF penetration. Great pharmacokinetics.Treats coccidioides.
Dx stain for Cryto
Narrow base budding
HIV Finger nail infection
Athletes foot
When in serum grows pseudohyphae. Retinal presentations
Rapid O2 desaturation upon exertion. Life threatening pneumonia in AIDS. Ubiquitous
Drug addict, diabetic w/ ketoacidosis, Bone transplant recipient, Renal Failure. Black necrosis of the ororpharynx. Rapid presentation
Bind to fungal heme iron in cytochrome P-450
Fungal infection that runs along lymphatic vessel. Rose growers disease
Bone fungal infections
Ubiquitous with hyphae branching at acute angles
Treats ring worm and nail infections. Inhibits nucleic acid synthesis
diaper rash
Anti-fungal with 3 fluorides. Tx for aspergillus. S/E - Bone pain, alteration in electroretinogram, increased alkaline phos, periostitis, Visual scatoma. Multiple drug interactions
Low Alkaline phosphatase, LDH less than 300, Leukocytopenia. Diagnosed via urine serology
Verrucous/warty skin lesions in cooler areas (tip of nose, fingers)
Fungal infection causing baldness
candida strain resistant to azoles
Immunecompromised w/ old dressings or IVs mucormycosis
Broad base budding, In soil. Great lakes. Beavers. Hits Normal immune systems. Fisherman, campers, hunters
Antifungal drug whose mechanism is similar to that of penicillin to bacteria. Tx for candida and aspergillus.
Need to suppliment with potassium, magnesium and EPO because of its renal toxicity.
Ring worm
Parental drug addict mucormycosis
Tx for histoplasmosis, spirotrichosis, and blastomyces. Taken with food/coca cola. Side effects: Adrenal excess (edema, hypertension, hypokalemia) nausea, vomiting. Long term - per
QuestionAnswerAdditional information
prophylaxis for pneumocystis and toxoplasmosis
Drug that is concentrated in the skin. Side effect is a loss of taste. Effective against dimorphic fungi in nails and skin
HIV, Thailand, Red pigment
Pseudo membrane in oropharynx - thrush.
Drug with multiple double bonds and intercalates into fungal plasma membranes creating lytic pores
Tx for Zygomycetes
Arizona/mexico border, Confussion/meningitis
Diabetic mucormycosis
Intracellular fungus, Spelunking, prisons, chicken coops
Skinny white male with COPD gets this fungal infection. pneumoia pericarditis, adrenal disease, adenocarcinoma like bowel lesions
Jock Rot 'well demarcated line'
Strain of cryptococcus that hits immunecompromised
right angle hyphae
Distal finger nail infection
Risk factor for yeast infection
Apical lung fungal ball
Massive laryngeal mass causing obstruction - South americam agricultural worker
Halo sign, wedge shaped pulmonary emboli infarct, immune compromised
Anti-fungal with Side effects of adrenal Insufficiency and hepatic necrosis. Needs gastric acid for absorption
MCC of fungal meningitis in AIDS pts. Pidgeon poop.
Strain of cryptococcus on the west coast and hits non-immuncompromised
Serology is terrible and is often false positive for histoplasmosis
Never use this for diagnosis of cryptococcus
Serology is great and should ALWAYS be followed
DNA synthesis inhibitor. Goes to the CNS. Can Cause hemorrhagic colitis and pancytopenia
Side effects are: Shake and Bake (fever chills, headache, nausea, vomiting) mediated through release of prostaglandin E. Renal toxicity is closely watched.
Dose dependent Candida strain
Bone marrow recipients/leukemic pts. mucormycosis

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