Infectious Disease Block 6 - Fungus

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Can you name the Infectious Disease Block 6?

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QuestionAnswerAdditional information
Low Alkaline phosphatase, LDH less than 300, Leukocytopenia. Diagnosed via urine serology
Ring worm
diaper rash
Fungal infection causing baldness
Athletes foot
Serology is great and should ALWAYS be followed
Side effects are: Shake and Bake (fever chills, headache, nausea, vomiting) mediated through release of prostaglandin E. Renal toxicity is closely watched.
right angle hyphae
Ubiquitous with hyphae branching at acute angles
Dose dependent Candida strain
Antifungal to treat fungal UTI's and has CSF penetration. Great pharmacokinetics.Treats coccidioides.
Anti-fungal with Side effects of adrenal Insufficiency and hepatic necrosis. Needs gastric acid for absorption
Dx stain for Cryto
HIV Finger nail infection
Diabetic mucormycosis
Intracellular fungus, Spelunking, prisons, chicken coops
prophylaxis for pneumocystis and toxoplasmosis
Massive laryngeal mass causing obstruction - South americam agricultural worker
Strain of cryptococcus that hits immunecompromised
DNA synthesis inhibitor. Goes to the CNS. Can Cause hemorrhagic colitis and pancytopenia
Tx for cryptococcus meningitis (Abv.)
Apical lung fungal ball
Halo sign, wedge shaped pulmonary emboli infarct, immune compromised
Serology is terrible and is often false positive for histoplasmosis
Bone fungal infections
Bind to fungal heme iron in cytochrome P-450
Fungal infection that runs along lymphatic vessel. Rose growers disease
Broad base budding, In soil. Great lakes. Beavers. Hits Normal immune systems. Fisherman, campers, hunters
QuestionAnswerAdditional information
candida strain resistant to azoles
MCC of fungal meningitis in AIDS pts. Pidgeon poop.
Drug addict, diabetic w/ ketoacidosis, Bone transplant recipient, Renal Failure. Black necrosis of the ororpharynx. Rapid presentation
Parental drug addict mucormycosis
Verrucous/warty skin lesions in cooler areas (tip of nose, fingers)
Drug that is concentrated in the skin. Side effect is a loss of taste. Effective against dimorphic fungi in nails and skin
Immunecompromised w/ old dressings or IVs mucormycosis
Distal finger nail infection
Treats ring worm and nail infections. Inhibits nucleic acid synthesis
Risk factor for yeast infection
Need to suppliment with potassium, magnesium and EPO because of its renal toxicity.
Anti-fungal with 3 fluorides. Tx for aspergillus. S/E - Bone pain, alteration in electroretinogram, increased alkaline phos, periostitis, Visual scatoma. Multiple drug interactions
Tx for Zygomycetes
Drug with multiple double bonds and intercalates into fungal plasma membranes creating lytic pores
HIV, Thailand, Red pigment
Bone marrow recipients/leukemic pts. mucormycosis
Jock Rot 'well demarcated line'
Tx for histoplasmosis, spirotrichosis, and blastomyces. Taken with food/coca cola. Side effects: Adrenal excess (edema, hypertension, hypokalemia) nausea, vomiting. Long term - per
Antifungal drug whose mechanism is similar to that of penicillin to bacteria. Tx for candida and aspergillus.
Rapid O2 desaturation upon exertion. Life threatening pneumonia in AIDS. Ubiquitous
Narrow base budding
erythema nodosum, hilar adenopathy. Apical cavitary disease. Dark skin and pregnancy are risk factors. Meningitis = Tx for life
Skinny white male with COPD gets this fungal infection. pneumoia pericarditis, adrenal disease, adenocarcinoma like bowel lesions
Never use this for diagnosis of cryptococcus
When in serum grows pseudohyphae. Retinal presentations
Arizona/mexico border, Confussion/meningitis
Strain of cryptococcus on the west coast and hits non-immuncompromised
Pseudo membrane in oropharynx - thrush.

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