Infectious Disease Block 6 - Fungus

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Can you name the Infectious Disease Block 6?

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QuestionAnswerAdditional information
Anti-fungal with Side effects of adrenal Insufficiency and hepatic necrosis. Needs gastric acid for absorption
Never use this for diagnosis of cryptococcus
HIV, Thailand, Red pigment
Halo sign, wedge shaped pulmonary emboli infarct, immune compromised
Tx for Zygomycetes
Drug that is concentrated in the skin. Side effect is a loss of taste. Effective against dimorphic fungi in nails and skin
Intracellular fungus, Spelunking, prisons, chicken coops
Dose dependent Candida strain
Serology is great and should ALWAYS be followed
Risk factor for yeast infection
Antifungal drug whose mechanism is similar to that of penicillin to bacteria. Tx for candida and aspergillus.
MCC of fungal meningitis in AIDS pts. Pidgeon poop.
Need to suppliment with potassium, magnesium and EPO because of its renal toxicity.
Pseudo membrane in oropharynx - thrush.
Distal finger nail infection
Verrucous/warty skin lesions in cooler areas (tip of nose, fingers)
Drug with multiple double bonds and intercalates into fungal plasma membranes creating lytic pores
Immunecompromised w/ old dressings or IVs mucormycosis
Dx stain for Cryto
Narrow base budding
Tx for cryptococcus meningitis (Abv.)
Arizona/mexico border, Confussion/meningitis
Fungal infection causing baldness
Strain of cryptococcus that hits immunecompromised
When in serum grows pseudohyphae. Retinal presentations
Apical lung fungal ball
Jock Rot 'well demarcated line'
candida strain resistant to azoles
QuestionAnswerAdditional information
Diabetic mucormycosis
Side effects are: Shake and Bake (fever chills, headache, nausea, vomiting) mediated through release of prostaglandin E. Renal toxicity is closely watched.
Rapid O2 desaturation upon exertion. Life threatening pneumonia in AIDS. Ubiquitous
Massive laryngeal mass causing obstruction - South americam agricultural worker
diaper rash
Strain of cryptococcus on the west coast and hits non-immuncompromised
DNA synthesis inhibitor. Goes to the CNS. Can Cause hemorrhagic colitis and pancytopenia
Bone fungal infections
prophylaxis for pneumocystis and toxoplasmosis
Fungal infection that runs along lymphatic vessel. Rose growers disease
Bind to fungal heme iron in cytochrome P-450
HIV Finger nail infection
Broad base budding, In soil. Great lakes. Beavers. Hits Normal immune systems. Fisherman, campers, hunters
erythema nodosum, hilar adenopathy. Apical cavitary disease. Dark skin and pregnancy are risk factors. Meningitis = Tx for life
Anti-fungal with 3 fluorides. Tx for aspergillus. S/E - Bone pain, alteration in electroretinogram, increased alkaline phos, periostitis, Visual scatoma. Multiple drug interactions
Athletes foot
Parental drug addict mucormycosis
Low Alkaline phosphatase, LDH less than 300, Leukocytopenia. Diagnosed via urine serology
Bone marrow recipients/leukemic pts. mucormycosis
Serology is terrible and is often false positive for histoplasmosis
Tx for histoplasmosis, spirotrichosis, and blastomyces. Taken with food/coca cola. Side effects: Adrenal excess (edema, hypertension, hypokalemia) nausea, vomiting. Long term - per
Treats ring worm and nail infections. Inhibits nucleic acid synthesis
Drug addict, diabetic w/ ketoacidosis, Bone transplant recipient, Renal Failure. Black necrosis of the ororpharynx. Rapid presentation
right angle hyphae
Skinny white male with COPD gets this fungal infection. pneumoia pericarditis, adrenal disease, adenocarcinoma like bowel lesions
Antifungal to treat fungal UTI's and has CSF penetration. Great pharmacokinetics.Treats coccidioides.
Ubiquitous with hyphae branching at acute angles
Ring worm

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