Infectious Disease Block 6 - Fungus

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Can you name the Infectious Disease Block 6?

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QuestionAnswerAdditional information
Diabetic mucormycosis
prophylaxis for pneumocystis and toxoplasmosis
Tx for cryptococcus meningitis (Abv.)
Bone fungal infections
Parental drug addict mucormycosis
Side effects are: Shake and Bake (fever chills, headache, nausea, vomiting) mediated through release of prostaglandin E. Renal toxicity is closely watched.
DNA synthesis inhibitor. Goes to the CNS. Can Cause hemorrhagic colitis and pancytopenia
Antifungal drug whose mechanism is similar to that of penicillin to bacteria. Tx for candida and aspergillus.
Low Alkaline phosphatase, LDH less than 300, Leukocytopenia. Diagnosed via urine serology
Tx for Zygomycetes
Drug that is concentrated in the skin. Side effect is a loss of taste. Effective against dimorphic fungi in nails and skin
Bind to fungal heme iron in cytochrome P-450
right angle hyphae
Ubiquitous with hyphae branching at acute angles
Fungal infection that runs along lymphatic vessel. Rose growers disease
Athletes foot
HIV, Thailand, Red pigment
Narrow base budding
Tx for histoplasmosis, spirotrichosis, and blastomyces. Taken with food/coca cola. Side effects: Adrenal excess (edema, hypertension, hypokalemia) nausea, vomiting. Long term - per
Dx stain for Cryto
Antifungal to treat fungal UTI's and has CSF penetration. Great pharmacokinetics.Treats coccidioides.
Drug with multiple double bonds and intercalates into fungal plasma membranes creating lytic pores
Serology is great and should ALWAYS be followed
Halo sign, wedge shaped pulmonary emboli infarct, immune compromised
Rapid O2 desaturation upon exertion. Life threatening pneumonia in AIDS. Ubiquitous
Massive laryngeal mass causing obstruction - South americam agricultural worker
Need to suppliment with potassium, magnesium and EPO because of its renal toxicity.
MCC of fungal meningitis in AIDS pts. Pidgeon poop.
QuestionAnswerAdditional information
Broad base budding, In soil. Great lakes. Beavers. Hits Normal immune systems. Fisherman, campers, hunters
Jock Rot 'well demarcated line'
Drug addict, diabetic w/ ketoacidosis, Bone transplant recipient, Renal Failure. Black necrosis of the ororpharynx. Rapid presentation
Apical lung fungal ball
Strain of cryptococcus that hits immunecompromised
Immunecompromised w/ old dressings or IVs mucormycosis
Fungal infection causing baldness
Dose dependent Candida strain
Intracellular fungus, Spelunking, prisons, chicken coops
Ring worm
Pseudo membrane in oropharynx - thrush.
Risk factor for yeast infection
erythema nodosum, hilar adenopathy. Apical cavitary disease. Dark skin and pregnancy are risk factors. Meningitis = Tx for life
Arizona/mexico border, Confussion/meningitis
Anti-fungal with 3 fluorides. Tx for aspergillus. S/E - Bone pain, alteration in electroretinogram, increased alkaline phos, periostitis, Visual scatoma. Multiple drug interactions
Treats ring worm and nail infections. Inhibits nucleic acid synthesis
Never use this for diagnosis of cryptococcus
HIV Finger nail infection
Anti-fungal with Side effects of adrenal Insufficiency and hepatic necrosis. Needs gastric acid for absorption
Verrucous/warty skin lesions in cooler areas (tip of nose, fingers)
When in serum grows pseudohyphae. Retinal presentations
Skinny white male with COPD gets this fungal infection. pneumoia pericarditis, adrenal disease, adenocarcinoma like bowel lesions
Distal finger nail infection
diaper rash
Serology is terrible and is often false positive for histoplasmosis
candida strain resistant to azoles
Bone marrow recipients/leukemic pts. mucormycosis
Strain of cryptococcus on the west coast and hits non-immuncompromised

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