Infectious Disease Block 6 - Fungus

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Can you name the Infectious Disease Block 6?

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QuestionAnswerAdditional information
Treats ring worm and nail infections. Inhibits nucleic acid synthesis
Drug addict, diabetic w/ ketoacidosis, Bone transplant recipient, Renal Failure. Black necrosis of the ororpharynx. Rapid presentation
Never use this for diagnosis of cryptococcus
DNA synthesis inhibitor. Goes to the CNS. Can Cause hemorrhagic colitis and pancytopenia
erythema nodosum, hilar adenopathy. Apical cavitary disease. Dark skin and pregnancy are risk factors. Meningitis = Tx for life
Pseudo membrane in oropharynx - thrush.
Anti-fungal with 3 fluorides. Tx for aspergillus. S/E - Bone pain, alteration in electroretinogram, increased alkaline phos, periostitis, Visual scatoma. Multiple drug interactions
Risk factor for yeast infection
HIV Finger nail infection
Strain of cryptococcus on the west coast and hits non-immuncompromised
Tx for histoplasmosis, spirotrichosis, and blastomyces. Taken with food/coca cola. Side effects: Adrenal excess (edema, hypertension, hypokalemia) nausea, vomiting. Long term - per
diaper rash
Distal finger nail infection
Antifungal drug whose mechanism is similar to that of penicillin to bacteria. Tx for candida and aspergillus.
Serology is terrible and is often false positive for histoplasmosis
Athletes foot
Arizona/mexico border, Confussion/meningitis
prophylaxis for pneumocystis and toxoplasmosis
Broad base budding, In soil. Great lakes. Beavers. Hits Normal immune systems. Fisherman, campers, hunters
Bone fungal infections
Low Alkaline phosphatase, LDH less than 300, Leukocytopenia. Diagnosed via urine serology
Bone marrow recipients/leukemic pts. mucormycosis
candida strain resistant to azoles
Halo sign, wedge shaped pulmonary emboli infarct, immune compromised
Intracellular fungus, Spelunking, prisons, chicken coops
HIV, Thailand, Red pigment
Apical lung fungal ball
Anti-fungal with Side effects of adrenal Insufficiency and hepatic necrosis. Needs gastric acid for absorption
QuestionAnswerAdditional information
Side effects are: Shake and Bake (fever chills, headache, nausea, vomiting) mediated through release of prostaglandin E. Renal toxicity is closely watched.
Fungal infection causing baldness
right angle hyphae
Verrucous/warty skin lesions in cooler areas (tip of nose, fingers)
Ring worm
Immunecompromised w/ old dressings or IVs mucormycosis
Tx for Zygomycetes
Tx for cryptococcus meningitis (Abv.)
Dose dependent Candida strain
When in serum grows pseudohyphae. Retinal presentations
Ubiquitous with hyphae branching at acute angles
Fungal infection that runs along lymphatic vessel. Rose growers disease
Bind to fungal heme iron in cytochrome P-450
Parental drug addict mucormycosis
Dx stain for Cryto
MCC of fungal meningitis in AIDS pts. Pidgeon poop.
Need to suppliment with potassium, magnesium and EPO because of its renal toxicity.
Antifungal to treat fungal UTI's and has CSF penetration. Great pharmacokinetics.Treats coccidioides.
Rapid O2 desaturation upon exertion. Life threatening pneumonia in AIDS. Ubiquitous
Narrow base budding
Diabetic mucormycosis
Drug that is concentrated in the skin. Side effect is a loss of taste. Effective against dimorphic fungi in nails and skin
Serology is great and should ALWAYS be followed
Massive laryngeal mass causing obstruction - South americam agricultural worker
Strain of cryptococcus that hits immunecompromised
Jock Rot 'well demarcated line'
Drug with multiple double bonds and intercalates into fungal plasma membranes creating lytic pores
Skinny white male with COPD gets this fungal infection. pneumoia pericarditis, adrenal disease, adenocarcinoma like bowel lesions

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