Infectious Disease Block 6 - Fungus

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Can you name the Infectious Disease Block 6?

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QuestionAnswerAdditional information
Tx for cryptococcus meningitis (Abv.)
Narrow base budding
Side effects are: Shake and Bake (fever chills, headache, nausea, vomiting) mediated through release of prostaglandin E. Renal toxicity is closely watched.
erythema nodosum, hilar adenopathy. Apical cavitary disease. Dark skin and pregnancy are risk factors. Meningitis = Tx for life
HIV Finger nail infection
Drug addict, diabetic w/ ketoacidosis, Bone transplant recipient, Renal Failure. Black necrosis of the ororpharynx. Rapid presentation
Need to suppliment with potassium, magnesium and EPO because of its renal toxicity.
diaper rash
Athletes foot
Verrucous/warty skin lesions in cooler areas (tip of nose, fingers)
Jock Rot 'well demarcated line'
Treats ring worm and nail infections. Inhibits nucleic acid synthesis
Immunecompromised w/ old dressings or IVs mucormycosis
Rapid O2 desaturation upon exertion. Life threatening pneumonia in AIDS. Ubiquitous
Fungal infection that runs along lymphatic vessel. Rose growers disease
Bind to fungal heme iron in cytochrome P-450
HIV, Thailand, Red pigment
When in serum grows pseudohyphae. Retinal presentations
Strain of cryptococcus on the west coast and hits non-immuncompromised
Tx for histoplasmosis, spirotrichosis, and blastomyces. Taken with food/coca cola. Side effects: Adrenal excess (edema, hypertension, hypokalemia) nausea, vomiting. Long term - per
Tx for Zygomycetes
Never use this for diagnosis of cryptococcus
Ubiquitous with hyphae branching at acute angles
Diabetic mucormycosis
Bone fungal infections
Skinny white male with COPD gets this fungal infection. pneumoia pericarditis, adrenal disease, adenocarcinoma like bowel lesions
Antifungal to treat fungal UTI's and has CSF penetration. Great pharmacokinetics.Treats coccidioides.
Intracellular fungus, Spelunking, prisons, chicken coops
QuestionAnswerAdditional information
Fungal infection causing baldness
candida strain resistant to azoles
Strain of cryptococcus that hits immunecompromised
Bone marrow recipients/leukemic pts. mucormycosis
Ring worm
Serology is terrible and is often false positive for histoplasmosis
Drug with multiple double bonds and intercalates into fungal plasma membranes creating lytic pores
Anti-fungal with 3 fluorides. Tx for aspergillus. S/E - Bone pain, alteration in electroretinogram, increased alkaline phos, periostitis, Visual scatoma. Multiple drug interactions
Antifungal drug whose mechanism is similar to that of penicillin to bacteria. Tx for candida and aspergillus.
prophylaxis for pneumocystis and toxoplasmosis
Massive laryngeal mass causing obstruction - South americam agricultural worker
Drug that is concentrated in the skin. Side effect is a loss of taste. Effective against dimorphic fungi in nails and skin
Risk factor for yeast infection
Serology is great and should ALWAYS be followed
Low Alkaline phosphatase, LDH less than 300, Leukocytopenia. Diagnosed via urine serology
Dose dependent Candida strain
right angle hyphae
Parental drug addict mucormycosis
Arizona/mexico border, Confussion/meningitis
Halo sign, wedge shaped pulmonary emboli infarct, immune compromised
Pseudo membrane in oropharynx - thrush.
Broad base budding, In soil. Great lakes. Beavers. Hits Normal immune systems. Fisherman, campers, hunters
Distal finger nail infection
MCC of fungal meningitis in AIDS pts. Pidgeon poop.
Apical lung fungal ball
Dx stain for Cryto
DNA synthesis inhibitor. Goes to the CNS. Can Cause hemorrhagic colitis and pancytopenia
Anti-fungal with Side effects of adrenal Insufficiency and hepatic necrosis. Needs gastric acid for absorption

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