Infectious Disease Block 6 - Fungus

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Can you name the Infectious Disease Block 6?

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Arizona/mexico border, Confussion/meningitis
Apical lung fungal ball
Tx for cryptococcus meningitis (Abv.)
Side effects are: Shake and Bake (fever chills, headache, nausea, vomiting) mediated through release of prostaglandin E. Renal toxicity is closely watched.
Massive laryngeal mass causing obstruction - South americam agricultural worker
erythema nodosum, hilar adenopathy. Apical cavitary disease. Dark skin and pregnancy are risk factors. Meningitis = Tx for life
Drug that is concentrated in the skin. Side effect is a loss of taste. Effective against dimorphic fungi in nails and skin
Bone marrow recipients/leukemic pts. mucormycosis
Low Alkaline phosphatase, LDH less than 300, Leukocytopenia. Diagnosed via urine serology
DNA synthesis inhibitor. Goes to the CNS. Can Cause hemorrhagic colitis and pancytopenia
Serology is great and should ALWAYS be followed
Tx for histoplasmosis, spirotrichosis, and blastomyces. Taken with food/coca cola. Side effects: Adrenal excess (edema, hypertension, hypokalemia) nausea, vomiting. Long term - per
Halo sign, wedge shaped pulmonary emboli infarct, immune compromised
Narrow base budding
HIV, Thailand, Red pigment
right angle hyphae
Distal finger nail infection
Antifungal to treat fungal UTI's and has CSF penetration. Great pharmacokinetics.Treats coccidioides.
Bone fungal infections
Treats ring worm and nail infections. Inhibits nucleic acid synthesis
Parental drug addict mucormycosis
Fungal infection that runs along lymphatic vessel. Rose growers disease
Fungal infection causing baldness
Drug with multiple double bonds and intercalates into fungal plasma membranes creating lytic pores
Verrucous/warty skin lesions in cooler areas (tip of nose, fingers)
Athletes foot
Pseudo membrane in oropharynx - thrush.
Never use this for diagnosis of cryptococcus
QuestionAnswerAdditional information
Dx stain for Cryto
Strain of cryptococcus on the west coast and hits non-immuncompromised
Drug addict, diabetic w/ ketoacidosis, Bone transplant recipient, Renal Failure. Black necrosis of the ororpharynx. Rapid presentation
Strain of cryptococcus that hits immunecompromised
Anti-fungal with 3 fluorides. Tx for aspergillus. S/E - Bone pain, alteration in electroretinogram, increased alkaline phos, periostitis, Visual scatoma. Multiple drug interactions
Jock Rot 'well demarcated line'
prophylaxis for pneumocystis and toxoplasmosis
Tx for Zygomycetes
Intracellular fungus, Spelunking, prisons, chicken coops
Broad base budding, In soil. Great lakes. Beavers. Hits Normal immune systems. Fisherman, campers, hunters
Ring worm
Need to suppliment with potassium, magnesium and EPO because of its renal toxicity.
Diabetic mucormycosis
Antifungal drug whose mechanism is similar to that of penicillin to bacteria. Tx for candida and aspergillus.
Anti-fungal with Side effects of adrenal Insufficiency and hepatic necrosis. Needs gastric acid for absorption
diaper rash
When in serum grows pseudohyphae. Retinal presentations
Serology is terrible and is often false positive for histoplasmosis
Rapid O2 desaturation upon exertion. Life threatening pneumonia in AIDS. Ubiquitous
MCC of fungal meningitis in AIDS pts. Pidgeon poop.
Ubiquitous with hyphae branching at acute angles
Immunecompromised w/ old dressings or IVs mucormycosis
HIV Finger nail infection
candida strain resistant to azoles
Dose dependent Candida strain
Skinny white male with COPD gets this fungal infection. pneumoia pericarditis, adrenal disease, adenocarcinoma like bowel lesions
Bind to fungal heme iron in cytochrome P-450
Risk factor for yeast infection

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Created Jun 23, 2012ReportNominate
Tags:block, disease, fungus, infection