Infectious Disease Block 6 - Fungus

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Can you name the Infectious Disease Block 6?

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QuestionAnswerAdditional information
Low Alkaline phosphatase, LDH less than 300, Leukocytopenia. Diagnosed via urine serology
Tx for histoplasmosis, spirotrichosis, and blastomyces. Taken with food/coca cola. Side effects: Adrenal excess (edema, hypertension, hypokalemia) nausea, vomiting. Long term - per
Strain of cryptococcus that hits immunecompromised
MCC of fungal meningitis in AIDS pts. Pidgeon poop.
Bone marrow recipients/leukemic pts. mucormycosis
Jock Rot 'well demarcated line'
candida strain resistant to azoles
right angle hyphae
Narrow base budding
Side effects are: Shake and Bake (fever chills, headache, nausea, vomiting) mediated through release of prostaglandin E. Renal toxicity is closely watched.
Tx for Zygomycetes
Dose dependent Candida strain
Arizona/mexico border, Confussion/meningitis
Apical lung fungal ball
erythema nodosum, hilar adenopathy. Apical cavitary disease. Dark skin and pregnancy are risk factors. Meningitis = Tx for life
Bind to fungal heme iron in cytochrome P-450
Ubiquitous with hyphae branching at acute angles
Dx stain for Cryto
diaper rash
Bone fungal infections
Broad base budding, In soil. Great lakes. Beavers. Hits Normal immune systems. Fisherman, campers, hunters
When in serum grows pseudohyphae. Retinal presentations
HIV, Thailand, Red pigment
Intracellular fungus, Spelunking, prisons, chicken coops
Drug with multiple double bonds and intercalates into fungal plasma membranes creating lytic pores
Ring worm
Skinny white male with COPD gets this fungal infection. pneumoia pericarditis, adrenal disease, adenocarcinoma like bowel lesions
Treats ring worm and nail infections. Inhibits nucleic acid synthesis
QuestionAnswerAdditional information
Antifungal drug whose mechanism is similar to that of penicillin to bacteria. Tx for candida and aspergillus.
DNA synthesis inhibitor. Goes to the CNS. Can Cause hemorrhagic colitis and pancytopenia
HIV Finger nail infection
Fungal infection causing baldness
Anti-fungal with 3 fluorides. Tx for aspergillus. S/E - Bone pain, alteration in electroretinogram, increased alkaline phos, periostitis, Visual scatoma. Multiple drug interactions
Tx for cryptococcus meningitis (Abv.)
Drug addict, diabetic w/ ketoacidosis, Bone transplant recipient, Renal Failure. Black necrosis of the ororpharynx. Rapid presentation
Serology is great and should ALWAYS be followed
Pseudo membrane in oropharynx - thrush.
Parental drug addict mucormycosis
Strain of cryptococcus on the west coast and hits non-immuncompromised
Need to suppliment with potassium, magnesium and EPO because of its renal toxicity.
Halo sign, wedge shaped pulmonary emboli infarct, immune compromised
Massive laryngeal mass causing obstruction - South americam agricultural worker
Rapid O2 desaturation upon exertion. Life threatening pneumonia in AIDS. Ubiquitous
prophylaxis for pneumocystis and toxoplasmosis
Fungal infection that runs along lymphatic vessel. Rose growers disease
Immunecompromised w/ old dressings or IVs mucormycosis
Athletes foot
Anti-fungal with Side effects of adrenal Insufficiency and hepatic necrosis. Needs gastric acid for absorption
Serology is terrible and is often false positive for histoplasmosis
Verrucous/warty skin lesions in cooler areas (tip of nose, fingers)
Risk factor for yeast infection
Antifungal to treat fungal UTI's and has CSF penetration. Great pharmacokinetics.Treats coccidioides.
Never use this for diagnosis of cryptococcus
Distal finger nail infection
Diabetic mucormycosis
Drug that is concentrated in the skin. Side effect is a loss of taste. Effective against dimorphic fungi in nails and skin

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Created Jun 23, 2012ReportNominate
Tags:block, disease, fungus, infection