Infectious Disease Block 6 - Fungus

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Can you name the Infectious Disease Block 6?

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QuestionAnswerAdditional information
Parental drug addict mucormycosis
Diabetic mucormycosis
Rapid O2 desaturation upon exertion. Life threatening pneumonia in AIDS. Ubiquitous
Ring worm
Antifungal to treat fungal UTI's and has CSF penetration. Great pharmacokinetics.Treats coccidioides.
Strain of cryptococcus that hits immunecompromised
Low Alkaline phosphatase, LDH less than 300, Leukocytopenia. Diagnosed via urine serology
MCC of fungal meningitis in AIDS pts. Pidgeon poop.
Side effects are: Shake and Bake (fever chills, headache, nausea, vomiting) mediated through release of prostaglandin E. Renal toxicity is closely watched.
Bone marrow recipients/leukemic pts. mucormycosis
Anti-fungal with Side effects of adrenal Insufficiency and hepatic necrosis. Needs gastric acid for absorption
Skinny white male with COPD gets this fungal infection. pneumoia pericarditis, adrenal disease, adenocarcinoma like bowel lesions
Pseudo membrane in oropharynx - thrush.
Antifungal drug whose mechanism is similar to that of penicillin to bacteria. Tx for candida and aspergillus.
Tx for cryptococcus meningitis (Abv.)
Bind to fungal heme iron in cytochrome P-450
Intracellular fungus, Spelunking, prisons, chicken coops
Drug with multiple double bonds and intercalates into fungal plasma membranes creating lytic pores
Anti-fungal with 3 fluorides. Tx for aspergillus. S/E - Bone pain, alteration in electroretinogram, increased alkaline phos, periostitis, Visual scatoma. Multiple drug interactions
Risk factor for yeast infection
Dx stain for Cryto
Fungal infection that runs along lymphatic vessel. Rose growers disease
Distal finger nail infection
Jock Rot 'well demarcated line'
DNA synthesis inhibitor. Goes to the CNS. Can Cause hemorrhagic colitis and pancytopenia
When in serum grows pseudohyphae. Retinal presentations
Arizona/mexico border, Confussion/meningitis
Halo sign, wedge shaped pulmonary emboli infarct, immune compromised
QuestionAnswerAdditional information
Serology is great and should ALWAYS be followed
Massive laryngeal mass causing obstruction - South americam agricultural worker
Immunecompromised w/ old dressings or IVs mucormycosis
prophylaxis for pneumocystis and toxoplasmosis
Tx for Zygomycetes
diaper rash
right angle hyphae
Bone fungal infections
Never use this for diagnosis of cryptococcus
Strain of cryptococcus on the west coast and hits non-immuncompromised
Athletes foot
HIV Finger nail infection
erythema nodosum, hilar adenopathy. Apical cavitary disease. Dark skin and pregnancy are risk factors. Meningitis = Tx for life
Drug that is concentrated in the skin. Side effect is a loss of taste. Effective against dimorphic fungi in nails and skin
Need to suppliment with potassium, magnesium and EPO because of its renal toxicity.
Fungal infection causing baldness
Dose dependent Candida strain
candida strain resistant to azoles
Treats ring worm and nail infections. Inhibits nucleic acid synthesis
Drug addict, diabetic w/ ketoacidosis, Bone transplant recipient, Renal Failure. Black necrosis of the ororpharynx. Rapid presentation
Ubiquitous with hyphae branching at acute angles
Serology is terrible and is often false positive for histoplasmosis
Tx for histoplasmosis, spirotrichosis, and blastomyces. Taken with food/coca cola. Side effects: Adrenal excess (edema, hypertension, hypokalemia) nausea, vomiting. Long term - per
Narrow base budding
Apical lung fungal ball
HIV, Thailand, Red pigment
Verrucous/warty skin lesions in cooler areas (tip of nose, fingers)
Broad base budding, In soil. Great lakes. Beavers. Hits Normal immune systems. Fisherman, campers, hunters

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