Infectious Disease Block 6 - Fungus

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Can you name the Infectious Disease Block 6?

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QuestionAnswerAdditional information
MCC of fungal meningitis in AIDS pts. Pidgeon poop.
Pseudo membrane in oropharynx - thrush.
Skinny white male with COPD gets this fungal infection. pneumoia pericarditis, adrenal disease, adenocarcinoma like bowel lesions
Diabetic mucormycosis
Apical lung fungal ball
erythema nodosum, hilar adenopathy. Apical cavitary disease. Dark skin and pregnancy are risk factors. Meningitis = Tx for life
Tx for histoplasmosis, spirotrichosis, and blastomyces. Taken with food/coca cola. Side effects: Adrenal excess (edema, hypertension, hypokalemia) nausea, vomiting. Long term - per
Antifungal drug whose mechanism is similar to that of penicillin to bacteria. Tx for candida and aspergillus.
Ring worm
Distal finger nail infection
Bind to fungal heme iron in cytochrome P-450
When in serum grows pseudohyphae. Retinal presentations
Dose dependent Candida strain
Arizona/mexico border, Confussion/meningitis
Fungal infection causing baldness
Drug that is concentrated in the skin. Side effect is a loss of taste. Effective against dimorphic fungi in nails and skin
Anti-fungal with 3 fluorides. Tx for aspergillus. S/E - Bone pain, alteration in electroretinogram, increased alkaline phos, periostitis, Visual scatoma. Multiple drug interactions
Side effects are: Shake and Bake (fever chills, headache, nausea, vomiting) mediated through release of prostaglandin E. Renal toxicity is closely watched.
Never use this for diagnosis of cryptococcus
HIV Finger nail infection
Tx for cryptococcus meningitis (Abv.)
Bone marrow recipients/leukemic pts. mucormycosis
right angle hyphae
Low Alkaline phosphatase, LDH less than 300, Leukocytopenia. Diagnosed via urine serology
Tx for Zygomycetes
Serology is terrible and is often false positive for histoplasmosis
diaper rash
Jock Rot 'well demarcated line'
QuestionAnswerAdditional information
Ubiquitous with hyphae branching at acute angles
candida strain resistant to azoles
Drug with multiple double bonds and intercalates into fungal plasma membranes creating lytic pores
Halo sign, wedge shaped pulmonary emboli infarct, immune compromised
Bone fungal infections
Verrucous/warty skin lesions in cooler areas (tip of nose, fingers)
DNA synthesis inhibitor. Goes to the CNS. Can Cause hemorrhagic colitis and pancytopenia
Athletes foot
Antifungal to treat fungal UTI's and has CSF penetration. Great pharmacokinetics.Treats coccidioides.
Fungal infection that runs along lymphatic vessel. Rose growers disease
Drug addict, diabetic w/ ketoacidosis, Bone transplant recipient, Renal Failure. Black necrosis of the ororpharynx. Rapid presentation
Immunecompromised w/ old dressings or IVs mucormycosis
Parental drug addict mucormycosis
Strain of cryptococcus that hits immunecompromised
Strain of cryptococcus on the west coast and hits non-immuncompromised
Narrow base budding
Need to suppliment with potassium, magnesium and EPO because of its renal toxicity.
Dx stain for Cryto
Massive laryngeal mass causing obstruction - South americam agricultural worker
Risk factor for yeast infection
Rapid O2 desaturation upon exertion. Life threatening pneumonia in AIDS. Ubiquitous
Broad base budding, In soil. Great lakes. Beavers. Hits Normal immune systems. Fisherman, campers, hunters
Treats ring worm and nail infections. Inhibits nucleic acid synthesis
Intracellular fungus, Spelunking, prisons, chicken coops
prophylaxis for pneumocystis and toxoplasmosis
HIV, Thailand, Red pigment
Anti-fungal with Side effects of adrenal Insufficiency and hepatic necrosis. Needs gastric acid for absorption
Serology is great and should ALWAYS be followed

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Created Jun 23, 2012ReportNominate
Tags:block, disease, fungus, infection