Infectious Disease Block 6 - Fungus

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Can you name the Infectious Disease Block 6?

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MCC of fungal meningitis in AIDS pts. Pidgeon poop.
Halo sign, wedge shaped pulmonary emboli infarct, immune compromised
Need to suppliment with potassium, magnesium and EPO because of its renal toxicity.
Fungal infection causing baldness
Parental drug addict mucormycosis
Bone marrow recipients/leukemic pts. mucormycosis
Drug that is concentrated in the skin. Side effect is a loss of taste. Effective against dimorphic fungi in nails and skin
Serology is terrible and is often false positive for histoplasmosis
Distal finger nail infection
Low Alkaline phosphatase, LDH less than 300, Leukocytopenia. Diagnosed via urine serology
Fungal infection that runs along lymphatic vessel. Rose growers disease
Tx for histoplasmosis, spirotrichosis, and blastomyces. Taken with food/coca cola. Side effects: Adrenal excess (edema, hypertension, hypokalemia) nausea, vomiting. Long term - per
Athletes foot
Immunecompromised w/ old dressings or IVs mucormycosis
Ring worm
erythema nodosum, hilar adenopathy. Apical cavitary disease. Dark skin and pregnancy are risk factors. Meningitis = Tx for life
Arizona/mexico border, Confussion/meningitis
Side effects are: Shake and Bake (fever chills, headache, nausea, vomiting) mediated through release of prostaglandin E. Renal toxicity is closely watched.
Dx stain for Cryto
Drug addict, diabetic w/ ketoacidosis, Bone transplant recipient, Renal Failure. Black necrosis of the ororpharynx. Rapid presentation
prophylaxis for pneumocystis and toxoplasmosis
DNA synthesis inhibitor. Goes to the CNS. Can Cause hemorrhagic colitis and pancytopenia
Anti-fungal with 3 fluorides. Tx for aspergillus. S/E - Bone pain, alteration in electroretinogram, increased alkaline phos, periostitis, Visual scatoma. Multiple drug interactions
Treats ring worm and nail infections. Inhibits nucleic acid synthesis
Dose dependent Candida strain
HIV, Thailand, Red pigment
Tx for Zygomycetes
Narrow base budding
QuestionAnswerAdditional information
Verrucous/warty skin lesions in cooler areas (tip of nose, fingers)
right angle hyphae
Ubiquitous with hyphae branching at acute angles
Bone fungal infections
Skinny white male with COPD gets this fungal infection. pneumoia pericarditis, adrenal disease, adenocarcinoma like bowel lesions
candida strain resistant to azoles
Antifungal to treat fungal UTI's and has CSF penetration. Great pharmacokinetics.Treats coccidioides.
Pseudo membrane in oropharynx - thrush.
Never use this for diagnosis of cryptococcus
Strain of cryptococcus that hits immunecompromised
Strain of cryptococcus on the west coast and hits non-immuncompromised
Bind to fungal heme iron in cytochrome P-450
HIV Finger nail infection
Diabetic mucormycosis
Tx for cryptococcus meningitis (Abv.)
diaper rash
Massive laryngeal mass causing obstruction - South americam agricultural worker
Intracellular fungus, Spelunking, prisons, chicken coops
Broad base budding, In soil. Great lakes. Beavers. Hits Normal immune systems. Fisherman, campers, hunters
Jock Rot 'well demarcated line'
Rapid O2 desaturation upon exertion. Life threatening pneumonia in AIDS. Ubiquitous
Drug with multiple double bonds and intercalates into fungal plasma membranes creating lytic pores
Antifungal drug whose mechanism is similar to that of penicillin to bacteria. Tx for candida and aspergillus.
Risk factor for yeast infection
Anti-fungal with Side effects of adrenal Insufficiency and hepatic necrosis. Needs gastric acid for absorption
When in serum grows pseudohyphae. Retinal presentations
Serology is great and should ALWAYS be followed
Apical lung fungal ball

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