Infectious Disease Block 6 - Fungus

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Can you name the Infectious Disease Block 6?

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Anti-fungal with Side effects of adrenal Insufficiency and hepatic necrosis. Needs gastric acid for absorption
Risk factor for yeast infection
Antifungal drug whose mechanism is similar to that of penicillin to bacteria. Tx for candida and aspergillus.
Drug addict, diabetic w/ ketoacidosis, Bone transplant recipient, Renal Failure. Black necrosis of the ororpharynx. Rapid presentation
Drug that is concentrated in the skin. Side effect is a loss of taste. Effective against dimorphic fungi in nails and skin
Fungal infection that runs along lymphatic vessel. Rose growers disease
MCC of fungal meningitis in AIDS pts. Pidgeon poop.
Immunecompromised w/ old dressings or IVs mucormycosis
diaper rash
prophylaxis for pneumocystis and toxoplasmosis
Dx stain for Cryto
Verrucous/warty skin lesions in cooler areas (tip of nose, fingers)
Intracellular fungus, Spelunking, prisons, chicken coops
Bone marrow recipients/leukemic pts. mucormycosis
Anti-fungal with 3 fluorides. Tx for aspergillus. S/E - Bone pain, alteration in electroretinogram, increased alkaline phos, periostitis, Visual scatoma. Multiple drug interactions
erythema nodosum, hilar adenopathy. Apical cavitary disease. Dark skin and pregnancy are risk factors. Meningitis = Tx for life
Jock Rot 'well demarcated line'
Strain of cryptococcus on the west coast and hits non-immuncompromised
Rapid O2 desaturation upon exertion. Life threatening pneumonia in AIDS. Ubiquitous
Bind to fungal heme iron in cytochrome P-450
Broad base budding, In soil. Great lakes. Beavers. Hits Normal immune systems. Fisherman, campers, hunters
Serology is terrible and is often false positive for histoplasmosis
Ring worm
Tx for histoplasmosis, spirotrichosis, and blastomyces. Taken with food/coca cola. Side effects: Adrenal excess (edema, hypertension, hypokalemia) nausea, vomiting. Long term - per
Athletes foot
HIV, Thailand, Red pigment
When in serum grows pseudohyphae. Retinal presentations
Massive laryngeal mass causing obstruction - South americam agricultural worker
QuestionAnswerAdditional information
Tx for cryptococcus meningitis (Abv.)
DNA synthesis inhibitor. Goes to the CNS. Can Cause hemorrhagic colitis and pancytopenia
Serology is great and should ALWAYS be followed
Pseudo membrane in oropharynx - thrush.
Apical lung fungal ball
Dose dependent Candida strain
candida strain resistant to azoles
Drug with multiple double bonds and intercalates into fungal plasma membranes creating lytic pores
Diabetic mucormycosis
HIV Finger nail infection
Antifungal to treat fungal UTI's and has CSF penetration. Great pharmacokinetics.Treats coccidioides.
Treats ring worm and nail infections. Inhibits nucleic acid synthesis
right angle hyphae
Bone fungal infections
Halo sign, wedge shaped pulmonary emboli infarct, immune compromised
Skinny white male with COPD gets this fungal infection. pneumoia pericarditis, adrenal disease, adenocarcinoma like bowel lesions
Narrow base budding
Distal finger nail infection
Fungal infection causing baldness
Arizona/mexico border, Confussion/meningitis
Need to suppliment with potassium, magnesium and EPO because of its renal toxicity.
Tx for Zygomycetes
Strain of cryptococcus that hits immunecompromised
Ubiquitous with hyphae branching at acute angles
Low Alkaline phosphatase, LDH less than 300, Leukocytopenia. Diagnosed via urine serology
Side effects are: Shake and Bake (fever chills, headache, nausea, vomiting) mediated through release of prostaglandin E. Renal toxicity is closely watched.
Never use this for diagnosis of cryptococcus
Parental drug addict mucormycosis

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Created Jun 23, 2012ReportNominate
Tags:block, disease, fungus, infection