Infectious Disease Block 6 - Fungus

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Can you name the Infectious Disease Block 6?

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QuestionAnswerAdditional information
Fungal infection causing baldness
Bone marrow recipients/leukemic pts. mucormycosis
Verrucous/warty skin lesions in cooler areas (tip of nose, fingers)
Need to suppliment with potassium, magnesium and EPO because of its renal toxicity.
Serology is great and should ALWAYS be followed
Rapid O2 desaturation upon exertion. Life threatening pneumonia in AIDS. Ubiquitous
Bone fungal infections
Drug addict, diabetic w/ ketoacidosis, Bone transplant recipient, Renal Failure. Black necrosis of the ororpharynx. Rapid presentation
Drug with multiple double bonds and intercalates into fungal plasma membranes creating lytic pores
Strain of cryptococcus on the west coast and hits non-immuncompromised
candida strain resistant to azoles
Apical lung fungal ball
Dose dependent Candida strain
Immunecompromised w/ old dressings or IVs mucormycosis
right angle hyphae
Risk factor for yeast infection
Massive laryngeal mass causing obstruction - South americam agricultural worker
Ubiquitous with hyphae branching at acute angles
Anti-fungal with Side effects of adrenal Insufficiency and hepatic necrosis. Needs gastric acid for absorption
prophylaxis for pneumocystis and toxoplasmosis
Fungal infection that runs along lymphatic vessel. Rose growers disease
Athletes foot
Tx for histoplasmosis, spirotrichosis, and blastomyces. Taken with food/coca cola. Side effects: Adrenal excess (edema, hypertension, hypokalemia) nausea, vomiting. Long term - per
Anti-fungal with 3 fluorides. Tx for aspergillus. S/E - Bone pain, alteration in electroretinogram, increased alkaline phos, periostitis, Visual scatoma. Multiple drug interactions
Diabetic mucormycosis
Tx for Zygomycetes
Pseudo membrane in oropharynx - thrush.
Strain of cryptococcus that hits immunecompromised
QuestionAnswerAdditional information
Tx for cryptococcus meningitis (Abv.)
Side effects are: Shake and Bake (fever chills, headache, nausea, vomiting) mediated through release of prostaglandin E. Renal toxicity is closely watched.
Dx stain for Cryto
HIV Finger nail infection
Broad base budding, In soil. Great lakes. Beavers. Hits Normal immune systems. Fisherman, campers, hunters
Ring worm
erythema nodosum, hilar adenopathy. Apical cavitary disease. Dark skin and pregnancy are risk factors. Meningitis = Tx for life
diaper rash
Arizona/mexico border, Confussion/meningitis
Treats ring worm and nail infections. Inhibits nucleic acid synthesis
Jock Rot 'well demarcated line'
Skinny white male with COPD gets this fungal infection. pneumoia pericarditis, adrenal disease, adenocarcinoma like bowel lesions
Bind to fungal heme iron in cytochrome P-450
Narrow base budding
Never use this for diagnosis of cryptococcus
Antifungal drug whose mechanism is similar to that of penicillin to bacteria. Tx for candida and aspergillus.
Distal finger nail infection
MCC of fungal meningitis in AIDS pts. Pidgeon poop.
Low Alkaline phosphatase, LDH less than 300, Leukocytopenia. Diagnosed via urine serology
Parental drug addict mucormycosis
Antifungal to treat fungal UTI's and has CSF penetration. Great pharmacokinetics.Treats coccidioides.
Intracellular fungus, Spelunking, prisons, chicken coops
DNA synthesis inhibitor. Goes to the CNS. Can Cause hemorrhagic colitis and pancytopenia
Halo sign, wedge shaped pulmonary emboli infarct, immune compromised
HIV, Thailand, Red pigment
Drug that is concentrated in the skin. Side effect is a loss of taste. Effective against dimorphic fungi in nails and skin
When in serum grows pseudohyphae. Retinal presentations
Serology is terrible and is often false positive for histoplasmosis

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Created Jun 23, 2012ReportNominate
Tags:block, disease, fungus, infection