Infectious Disease Block 6 - Fungus

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Can you name the Infectious Disease Block 6?

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QuestionAnswerAdditional information
HIV Finger nail infection
Narrow base budding
Low Alkaline phosphatase, LDH less than 300, Leukocytopenia. Diagnosed via urine serology
Drug that is concentrated in the skin. Side effect is a loss of taste. Effective against dimorphic fungi in nails and skin
Need to suppliment with potassium, magnesium and EPO because of its renal toxicity.
Tx for histoplasmosis, spirotrichosis, and blastomyces. Taken with food/coca cola. Side effects: Adrenal excess (edema, hypertension, hypokalemia) nausea, vomiting. Long term - per
Serology is terrible and is often false positive for histoplasmosis
prophylaxis for pneumocystis and toxoplasmosis
Massive laryngeal mass causing obstruction - South americam agricultural worker
Distal finger nail infection
Tx for Zygomycetes
Tx for cryptococcus meningitis (Abv.)
Dose dependent Candida strain
Verrucous/warty skin lesions in cooler areas (tip of nose, fingers)
Fungal infection causing baldness
Antifungal drug whose mechanism is similar to that of penicillin to bacteria. Tx for candida and aspergillus.
Parental drug addict mucormycosis
When in serum grows pseudohyphae. Retinal presentations
HIV, Thailand, Red pigment
Dx stain for Cryto
Antifungal to treat fungal UTI's and has CSF penetration. Great pharmacokinetics.Treats coccidioides.
Broad base budding, In soil. Great lakes. Beavers. Hits Normal immune systems. Fisherman, campers, hunters
Athletes foot
right angle hyphae
Bind to fungal heme iron in cytochrome P-450
Side effects are: Shake and Bake (fever chills, headache, nausea, vomiting) mediated through release of prostaglandin E. Renal toxicity is closely watched.
Rapid O2 desaturation upon exertion. Life threatening pneumonia in AIDS. Ubiquitous
Risk factor for yeast infection
QuestionAnswerAdditional information
MCC of fungal meningitis in AIDS pts. Pidgeon poop.
Strain of cryptococcus that hits immunecompromised
Bone marrow recipients/leukemic pts. mucormycosis
Skinny white male with COPD gets this fungal infection. pneumoia pericarditis, adrenal disease, adenocarcinoma like bowel lesions
Immunecompromised w/ old dressings or IVs mucormycosis
Ring worm
DNA synthesis inhibitor. Goes to the CNS. Can Cause hemorrhagic colitis and pancytopenia
diaper rash
Arizona/mexico border, Confussion/meningitis
Halo sign, wedge shaped pulmonary emboli infarct, immune compromised
Anti-fungal with 3 fluorides. Tx for aspergillus. S/E - Bone pain, alteration in electroretinogram, increased alkaline phos, periostitis, Visual scatoma. Multiple drug interactions
Pseudo membrane in oropharynx - thrush.
Diabetic mucormycosis
Never use this for diagnosis of cryptococcus
Ubiquitous with hyphae branching at acute angles
Anti-fungal with Side effects of adrenal Insufficiency and hepatic necrosis. Needs gastric acid for absorption
Apical lung fungal ball
Jock Rot 'well demarcated line'
Drug addict, diabetic w/ ketoacidosis, Bone transplant recipient, Renal Failure. Black necrosis of the ororpharynx. Rapid presentation
Fungal infection that runs along lymphatic vessel. Rose growers disease
Drug with multiple double bonds and intercalates into fungal plasma membranes creating lytic pores
Bone fungal infections
candida strain resistant to azoles
Intracellular fungus, Spelunking, prisons, chicken coops
Treats ring worm and nail infections. Inhibits nucleic acid synthesis
erythema nodosum, hilar adenopathy. Apical cavitary disease. Dark skin and pregnancy are risk factors. Meningitis = Tx for life
Serology is great and should ALWAYS be followed
Strain of cryptococcus on the west coast and hits non-immuncompromised

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Created Jun 23, 2012ReportNominate
Tags:block, disease, fungus, infection