| Clues | World City | Letter |
| One of the world's oldest cities and the capital of Greece | |
| Largest city in New England and a type of 'cream pie' | |
| Near the Nile delta and the largest metro in Africa | |
| Known as the City of Mosques and is on the Dhaleswari River | |
| In the extreme west of Texas and home to the Franklin Mountains | |
| Largest city in the Italian region of Tuscany and home of Galileo Galilei | |
| Historically known as 'Canton' and the largest Chinese metro | |
| Largest city in the Caribbean and a major port in Cuba | |
| Formerly known as 'Constantinople' and you can't go back to 'Constantinople' | |
| Home of the Western Wall and located in the Judean Mountains | |
| Capital of Ukraine and founded in the 5th century | |
| Located on the Pacific Ocean and the fifth largest city in South America | |
| Second most visited English city and south of the Pennines | |
| Has five boroughs and is home to the Statue of Liberty | |
| Located on Honshū and in the region of the Keihanshin metro area | |
| Where you'll find the Eiffel Tower and is along on the Seine river | |
| In the same country as Guayaquil and the second highest world capital | |
| Located on the Tiber River and the neighbor of Vatican City | |
| Home to the Space Tower and is about 114 mi. south of Canada | |
| Capital of Ontario and is part of the 'Golden Horseshoe' subregion | |
| Largest city of the least densely populated country and founded in 1639 | |
| 9th largest city in the European Union and known as the 'City of Music' | |
| Home of the White House and the Lincoln Memorial | |
| One of the four historical capitals of China and along the Silk Road | |
| Former capital of Myanmar and has the most colonial buildings in Southeast Asia | |
| Largest city in Switzerland and one of the world's largest financial centers | |